2016.06-至今 中国科学院上海有机化学研究所金属有机化学国家重点实验室, 研究员
2012.11-2016.05 麻省理工学院化学系,博士后研究员（导师： Prof. Stephen L. Buchwald）
2011.10-2012.10 东京大学药学部, JSPS博士后研究员（导师： Prof. Motomu Kanai）
2008.10-2011.09 东京大学药学部, 博士（导师：Prof. Masakatsu Shibasaki and Prof. Motomu Kanai）
发展新型优势手性配体；发展新型高效的不对称催化反应；发展经济、绿色和高效的手性药物及药物中间体合成新工艺。
2023 国家杰出青年科学基金获得者
2022 上海市优秀学术带头人
2021 Bayer Investigator Award
2019 Thieme Chemistry Journals Award
2016 国家海外高层次人才计划
2016 中科院人才计划
1.Lin-Xin Ruan, Bo Sun, Jia-Ming Liu, Shi-Liang Shi*Dynamic kinetic asymmetricarylation and alkenylation of ketones. Science 2023, 379, 662？670.
2.Zi-Chao Wang#, Xiaohua Luo#, Jia-Wen Zhang#, Chen-Fei Liu#, Ming Joo Koh*, Shi-Liang Shi* Enantioselective C–C cross-coupling of unactivated alkenes. Nat. Catal. 2023, 6, 1087–1097.
3.Zi-Chao Wang, Jia-Wen Zhang, Ming Joo Koh*, Shi-Liang Shi* Divergent and Selective Light Alkene Cross-Coupling. Angew. Chem. Int. Ed., 2023, 62, e202310203.
4.Binyang Jiang, Jia-ming Liu, Shi-Liang Shi* Bifunctional NHC-Promoted C2-Alkylation of Pyridine via Ni–Al Bimetallic-Catalyzed Hydroarylation of Unactivated Alkenes. ACS Catal. 2023, 13, 6068-6075.
5. Zi-Chao Wang, Yan-Yu Li, Shuo-Qing Zhang, Xin Hong*, Shi-Liang Shi* Unsymmetric N-heterocyclic carbene ligand enabled nickel-catalysed arylation of bulky primary and secondary amines. Chem. Sci., 2023, 14, 4390-4396.
6.Chen-Fei Liu#, Zi-Chao Wang#, Xiaohua Luo#, Jiawei Lu, Charyl Hui Min Ko, Shi-Liang Shi*, Ming Joo Koh* Synthesis of tri- and tetrasubstituted stereocentres by nickel-catalysed enantioselective olefin cross-couplings. Nat. Catal. 2022, 5, 934-942.
7.Jun-Bao Ma, Xia Zhao, Dongju Zhang*, Shi-Liang Shi* Enantio- and Regioselective Ni-Catalyzed para-C-H Alkylation of Pyridines with Styrenes via Intermolecular Hydroarylation. J. Am. Chem. Soc. 2022, 144, 13643–13651.
8.Wu-Bin Zhang, Guang Chen, Shi-Liang Shi* Enantioselective Ni/N-Heterocyclic Carbene-Catalyzed Redox-Economical Coupling of Aldehydes, Alkynes, and Enones for Rapid Construction of Acyclic All-Carbon Quaternary Stereocenters. J. Am. Chem. Soc. 2022, 144, 130-136.
9.Zi-Chao Wang, Jian Gao, Yuan Cai, Xiaodong Ye, Shi-Liang Shi* Chemo- and Enantioselective Arylation and Alkenylation of Aldehydes Enabled by Nickel/N-Heterocyclic Carbene Catalysis. CCS Chem. 2022, 4, 1169–1179.
10.Binyang Jiang, Shi-Liang Shi* Pd-Catalyzed Cross-Coupling of Alkylzirconocenes and Aryl Chlorides. Chin. J. Chem. 2022, 40, 1813-1820.
11.Yuan Cai, Shi-Liang Shi* Enantioconvergent Arylation of Racemic Secondary Alcohols to Chiral Tertiary Alcohols Enabled by Nickel/N-Heterocyclic Carbene Catalysis. J. Am. Chem. Soc. 2021, 143, 11963-11968.
12.Zi-Chao Wang, Pei-Pei Xie, Youjun Xu, Xin Hong*, Shi-Liang Shi* Low-Temperature Ni-Catalyzed C-N Cross-Coupling via Kinetic Resolution Enabled by a Bulky yet Flexible Chiral N-Heterocyclic Carbene Ligand. Angew. Chem. Int. Ed. 2021, 60, 16077–16084.
13. Yuan Cai, Lin-Xin Ruan, Abdul Rahman, Shi-Liang Shi* Fast Enantio- and Chemoselective Arylation of Ketones with Organoboronic Esters Enabled by Nickel/NHC Catalysis. Angew. Chem., Int. Ed. 2021, 60, 5262–5267.
14.Yu-Qing Li, Feng Li, Shi-Liang Shi* Expedient Synthesis of Ketones via N-Heterocyclic Carbene/Nickel-Catalyzed Redox-Economical Coupling of Alcohols and Alkynes. Chin. J. Chem. 2020, 38, 1035-1039.
15.Wu-Bin Zhang, Xin-Tuo Yang, Jun-Bao Ma, Zhi-Min Su, Shi-Liang Shi* Regio- and Enantioselective C-H Cyclization of Pyridines with Alkenes Enabled by a Nickel/N-Heterocyclic Carbene Catalysis. J. Am. Chem. Soc. 2019, 141, 5628-5634.
16.Di Shen, Youjun Xu, Shi-Liang Shi* A Bulky Chiral N-Heterocyclic Carbene Palladium Catalyst Enables Highly Enantioselective Suzuki-Miyaura Cross-Coupling Reactions for the Synthesis of Biaryl Atropisomers. J. Am. Chem. Soc. 2019, 141, 14938-14945.
17.Yuan Cai, Xiaodong Ye, Sheng Liu, Shi-Liang Shi* Nickel/NHC-Catalyzed Asymmetric C–H Alkylation of Fluoroarenes with Alkenes: Synthesis of Enantioenriched Fluorotetralins. Angew. Chem. Int. Ed. 2019, 58, 13433-13437.
18.Yuan Cai, Jia-Wen Zhang, Feng Li, Jia-Ming Liu, Shi-Liang Shi* Nickel/N-Heterocyclic Carbene Complex-Catalyzed Enantioselective Redox-Neutral Coupling of Benzyl Alcohols and Alkynes to Allylic Alcohols. ACS Catal. 2019, 9, 1-6.
19.Yuan Cai, Xin-Tuo Yang, Shuo-Qin Zhang, Feng Li, Yu-Qin Li, Lin-Xin Ruan, Xin Hong*, Shi-Liang Shi* Copper-Catalyzed Enantioselective Markovnikov Protoboration of a-Olefins Enabled by a Buttressed N-Heterocyclic Carbene Ligand. Angew. Chem. Int. Ed. 2018, 57, 1376-1380.
