2006年4月-至今：研究员，中国科学院上海有机所金属有机国家重点实验室
2004年2月-2006年4月：Principal Investigator, Genomics Institute of the Novartis Research Foundation (GNF), San Diego, CA USA
2001年9月-2004年1月：Postdoctoral fellow (Advisor: Professor Jeffery W. Kelly), The Scripps Research Institute, La Jolla, CA USA
1996年9月-2001年7月：硕博研究生 （导师：戴立信院士），中国科学院上海有机所
1992年9月-1996年7月：本科学生，南开大学化学系
不对称催化、金属有机
绿色化学导向的新反应方法和技术
药物化学导向的新反应方法和技术
2024年Yoshida Prize
2024年度中国化学会黄耀曾金属有机化学奖
2023年首期新基石研究员项目
2019 年度科学探索奖
2019年中国化学会菁青化学卓越奖
2019年上海市化学化工学会庄长恭专项奖励基金
2019年第十六届上海市科技精英
2019年上海市青年科技杰出贡献奖
2017/2018年 Novartis Chemistry Lectureship
2017/2018年第九届中国化学会-巴斯夫公司青年知识创新奖
2017年第十二届上海市自然科学牡丹奖
2017年度国家自然科学奖二等奖（第一完成人）
2016年度上海市自然科学奖一等奖（第一完成人）
2016年度何梁何利基金青年创新奖
2016年第十四届中国青年科技奖
2015年英国皇家化学会默克奖
2014年上海领军人才
2014年药明康德生命化学研究奖
2014年第七届上海青年科技英才
2014年中国化学会青年手性化学奖
2014年罗氏中国青年科学家奖
2014年中国科学院青年科学家奖
2014年中国科学院上海分院第三届杰出青年科技创新人才
2011年阿斯利康杰出化学奖
2011年第三届中国化学会-英国皇家化学会青年化学奖
2010年Thieme Chemistry Journals Award
2008年中国化学会青年化学奖
2018年第一届“中美教授联合会杰出青年教授奖
2017年中国化学会－约翰威立出版公司青年化学论文奖
1. S.-L. You (2016) Asymmetric Dearomatization Reactions, Wiley-VCH.
2. S.-L. You (2015) Asymmetric Functionalization of C-H Bonds, Royal Society of Chemistry.
3. Yu, X.; Zheng, C.*; You, S.-L.* Chiral Brønsted Acid Catalyzed Intramolecular Asymmetric Dearomatization Reaction of Indoles with Cyclobutanones via Cascade Friedel–Crafts/Semipinacol Rearrangement. J. Am. Chem. Soc. 2024, 146, accepted.
4. Li, M.-Z.; Huang, X.-L.; Zhang, Z.-Y.; Wang, Z.; Wu, Z.; Yang, H.; Shen, W.-J.; Cheng, Y.-Z.*; You, S.-L.* Gd(III)-Catalyzed Regio-, Diastereo- and Enantioselective [4+2] Pho-tocycloaddition of Naphthalene Derivatives. J. Am. Chem. Soc. 2024, 146, 16982-16989.
5. Zheng, Y.; Xie, P.-P.; Zheng, C.*; You, S.-L.* Cobalt-Catalyzed Asymmetric Synthesis of Planar Chiral Ferrocene Derivatives via C(sp2)–C(sp3) Bond Formation. CCS Chem. 2024, 6, DOI: 10.31635/ccschem.024.202404231. (Zheng, Y. and Xie, P.-P. contribute equally)
6. Zhang, S.-S.; Wang, R.-X.; Gu, Q.; You, S.-L.* Phosphine-Catalyzed Asymmetric Dearomative [3+2] Annulation Reaction of Benzimidazoles with Cyclopropenones. CCS Chem. 2024, 6, DOI: 10.31635/ccschem.024.202403981.
7. Xu, S.-S.; Qiu, H.; Xie, P.-P.; Wang, Z.-H.; Wang, X.; Zheng, C.*; You, S.-L.*; Mei, T.-S.* Cobalt-Catalyzed Electrochemical Enantioselective Reductive Cross-Coupling of Organohalides. CCS Chem. 2024, 6, DOI: 10.31635/ccschem.024.202403939. (Xu, S.-S.; Qiu, H.; Xie, P.-P. and Wang, Z.-H. contribute equally)
8. Shlapakov, N. S.; Andrey D. Kobelev, A. D.; Burykina, J. V.; Cheng, Y.-Z.; You, S.-L.*; Ananikov, V. P.* Sulfur in Waste-Free Sustainable Synthesis: Advancing Carbon-Carbon Coupling Techniques. Angew. Chem. Int. Ed. 2024, 63, e202402109.
9. An, B.; Cui, H.; Zheng, C.*; Chen, J.-L.; Lan, F.; You, S.-L.*; Zhang, X.* Tunable C-H Functionalization and Dearomatization Enabled by an Organic Photocatalyst. Chem. Sci. 2024, 15, 4114-4120.
10. Zhu, M.; Gao, Y.-J.; Huang, X.-L.; Zheng, C.*; You, S.-L.* Photo-induced intramolecular dearomative [5 + 4] cycloaddition of arenes for the construction of highly strained medium-sized-rings. Nat. Commun. 2024, 15, 2462. (Zhu, M.; Gao, Y.-J.; and Huang, X.-L. contribute equally)
11. Song, H.; Li, M.; You, S.-L.* Z-Retentive Asymmetric Allylic Substitution Reactions of Aldimine Esters under Ru/Cu Dual Catalysis. J. Am. Chem. Soc. 2024, 146, 4333-4339.
12. Liu, J.; Cao, W.-B.; You, S.-L.* Ligand-Enabled Z-Retentive Tsuji-Trost Reaction. Chem 2024, 10, 1295-1305.
13. He, Y.-M.; Cheng, Y.-Z.; Duan, Y.; Zhang, Y.-D.; Fan, Q.-H.*; You, S.-L.*; Luo, S.*; Zhu, S.-F.*; Fu, X.-F.*; Zhou, Q.-L.* Recent Progress of Asymmetric Catalysis from a Chinese Perspective. CCS Chem. 2023, 5, 1442-1446.
14. Yang, P.-S.; Wang, R.-X.; Huang, X.-L.; Cheng, Y.-Z.; You, S.-L.* Enantioselective Synthesis of Cyclobutane Derivatives via Cascade Asymmetric Allylic Etherification/[2+2] Photocycloaddition. J. Am. Chem. Soc. 2023, 145, 21752-21759.
15. Liu, C.-X.; Zhao, F.; Gu, Q.; You, S.-L.* Enantioselective Rh(I)-Catalyzed C-H Arylation of Ferroceneformaldehydes. ACS Cent. Sci. 2023, 9, 2036-2043.
16. Liu, C.-X.; Yin, S.-Y.; Zhao, F.; Yang, H.; Feng, Z.; Gu, Q.; You, S.-L.* Rhodium-Catalyzed Asymmetric C-H Functionalization Reactions. Chem. Rev. 2023, 123, 10079-10134. (Liu, C.-X. and Yin, S.-Y. contribute equally)
17. Yin, S.-Y.; Zhou, Q.; Liu, C.-X.; Gu, Q.; You, S.-L.* Enantioselective Synthesis of N-N Biaryl Atropisomers through Iridium(I)-Catalyzed C-H Alkylation with Acrylates. Angew. Chem. Int. Ed. 2023, 62, e202305067.
18. Huang, X.-Y.; Xie, P.-P.; Zou, L.-M.; Zheng, C.*; You, S.-L.* Asymmetric Dearomatization of Indoles with Azodicarboxylates via Cascade Electrophilic Amination/aza-Prins Cyclization/Phenonium-like Rearrangement. J. Am. Chem. Soc. 2023, 145, 11745-11753. (Huang, X.-Y. and Xie, P.-P. contribute equally)
19. Zhang, W.-Y.; Wang, H.-C.; Wang, Y.; Zheng, C.*; You, S.-L.* Enantioselective Dearomatization of Indoles via SmI2-Mediated Intermolecular Reductive Coupling with Ketones. J. Am. Chem. Soc. 2023, 145, 10314-10321.
20. Liu, C.-X.; Xie, P.-P.; Zhao, F.; Wang, Q.; Feng, Z.; Wang, H.; Zheng, C.*; You, S.-L.* Explicit Mechanism of Rh(I)-Catalyzed Asymmetric C–H Arylation and Facile Synthesis of Planar Chiral Ferrocenophanes. J. Am. Chem. Soc. 2023, 145, 4765-4773. (Liu, C.-X. and Xie, P.-P. contribute equally)
21. Zheng, Y.; Zhang, W.-Y.; Gu, Q.; Zheng, C.*; You, S.-L.* Cobalt(III)-catalyzed asymmetric ring-opening of 7-oxabenzonorbornadienes via indole C–H functionalization. Nat. Commun. 2023, 14, 1094.
22. Xie, J.-H.; Hou, Y.-M.; Feng, Z.; You, S.-L.* Stereodivergent Construction of 1,3-Chiral Centers via Tandem Asymmetric Conjugate Addition and Allylic Substitution Reaction. Angew. Chem. Int. Ed. 2023, 62, e202216396.
23. Liu, C.-X.; Zhao, F.-N.; Feng, Z.; Wang, Q.; Gu, Q.; You, S.-L.* Kinetic resolution of planar chiral metallocenes using Rh-catalysed enantioselective C-H arylation. Nature Synthesis 2023, 2, 49-57.
24. Zhang, W.-W.; Wang, Q.; Zhang, S.-Z.; Zheng, C.*; You, S.-L.* SCp Rhodium-Catalyzed Asymmetric Satoh–Miura Reaction for Buildingup Axial Chirality: Counteranion-Directed Switching of Reaction Pathways. Angew. Chem. Int. Ed. 2023, 62, e202214460.
25. Yang, P.; Wang, R.-X.; Cheng, Y.-Z.; Zheng, C.; You, S.-L.* Iridium-Catalyzed Asymmetric Allylic Benzylation with Photogenerated Hydroxy-o-Quinodimethanes. Angew. Chem. Int. Ed. 2022, 61, e202213520.
26. Zhu, M.; Zhang, X.*; Zheng, C.*; You, S.-L.* Energy Transfer Enabled Dearomative Cycloaddition Reactions of In-doles/Pyrroles via Excited-State Aromatics. Acc. Chem. Res. 2022, 55, 2510-2525.
27. Zhao, K.; Kohnke, P.; Yang, Z.; Cheng, X.; You, S.-L.*; Zhang, L.* Enantioselective Dearomative Cyclization Enabled by Asymmetric Cooperative Gold Catalysis. Angew. Chem. Int. Ed. 2022, 61, e202207518.
28. Jiang R.; Zhao, Q.-R.; Zheng, C.*; You, S.-L.* Structurally well-defined anti-π-allyliridium complexes catalyse Z-retentive asymmetric allylic alkylation of oxindoles. Nature Catal. 2022, 5, 1089-1097.
29. Wan, Q.; Zheng, C.; Yuan, Y.-F.*; You, S.-L.* Ag2O/Squaramide Cocatalyzed Asymmetric Interrupted Barton-Zard Reaction of 8-Nitroimidazo[1,2-a]pyridines. Sci. Bull. 2022, 67, 1688-1695.
30. Ding, L.; Song, H.; Zheng, C.; You, S.-L.* Enantioselective Synthesis of Medium-sized-ring Lactones via Iridium-catalyzed Z-Retentive Asymmetric Allylic Substitution Reaction. J. Am. Chem. Soc. 2022, 144, 4770-4775.
31. Liu, X.-J.; Zhang, W.-Y.; Zheng, C.; You, S.-L.* Iridium-Catalyzed Asymmetric Allylic Substitution of Methyl Azaarenes. Angew. Chem. Int. Ed. 2022, e202200164. (Liu, X.-J. and Zhang, W.-Y. contribute equally)
32. Coppola, G. A.; Pillitteri, S.; Van der Eycken, E. V.*; You, S.-L.*; Sharma, U. K.* Multicomponent Reactions and Photo/Electrochemistry Join Forces: Atom Economy Meets Energy Efficiency. Chem. Soc. Rev. 2022, 51, 2313-2382.
33. Wang, Y.; Zhang, W.-Y.; Yu, Z.-L.; Zheng, C.; You, S.-L.* SmI2-mediated enantioselective reductive dearomatization of non-activated arenes. Nature Synthesis 2022, 1, 401-406. (Wang, Y. and Zhang, W.-Y. contribute equally)
34. Cheng, Y.-Z.; Feng, Z.; Zhang, X.*; You, S.-L.* Visible-Light Induced Dearomatization Reactions. Chem. Soc. Rev. 2022, 51, 2145-2170.
35. Liu, Y.-Z.; Song, H.; Zheng, C.*; You, S.-L.* Cascade Asymmetric Dearomative Cyclization Reactions via Transition-metal-catalysis. Nature Synthesis 2022, 1, 203-216. (Invited review)
36. Huang, Y.-Q.; Wu, Z.-J.; Zhu, L.; Gu, Q.; Lu, X.*; You, S.-L.*; Mei, T.-S.* Electrochemical Rhodium-Catalyzed Enantioselective C−H Annulation with Alkynes. CCS Chem. 2022, 4, 3181-3189.
37. Liu, C.-X.; Zhang, W.-W.; Yin, S.-Y.; Gu, Q.; You, S.-L.* Synthesis of atropisomers by transition-metal-catalyzed asymmetric C-H functionalization reactions. J. Am. Chem. Soc. 2021, 143, 14025-14040.
38. Zhu, M.; Huang, X.-L.; Sun, S.; Zheng, C.*; You, S.-L.* Visible-Light-Induced Dearomatization of Indoles/Pyrroles with Vinylcyclopropanes: Expedient Synthesis of Structurally Diverse Polycyclic Indolines/Pyrrolines. J. Am. Chem. Soc. 2021, 143, 13441-13449.
39. Xie, J.-H.; Zheng, C.; You, S.-L.* Palladium-Catalyzed Dearomative Alkoxyallylation of 3-Nitroindoles with Allyl Carbonates. Angew. Chem. Int. Ed. 2021, 60, 22184-22188.
40. Wan, Q.; Xie, J.-H.; Zheng, C.; Yuan, Y.-F.*; You, S.-L.* Ag-Catalyzed Asymmetric Dearomatization of Electron-deficient Heteroarenes via Interrupted Barton-Zard Reaction. Angew. Chem. Int. Ed. 2021, 60, 19730-19734.
41. Pan, C.; Yin, S.-Y.; Wang, S.-B.; Gu, Q.; You, S.-L.* Oxygen-linked Cyclopentadienyl Rh(III) Complexes-Catalyzed Asymmetric C−H Arylation of Benzo[h]quinolines with 1-Diazonaphthoquinones. Angew. Chem. Int. Ed. 2021, 60, 15510-15516.
42. Zheng, C.; You, S.-L.* Advances in Catalytic Asymmetric Dearomatization. ACS Cent. Sci. 2021, 7, 432-444.
43. Lin, Z.; Xue, Y.; Liang, X.; Wang, J.; Lin, S.; Tao, J.; You, S.-L.*; Liu, W.* Oxidative Indole Dearomatization for Asymmetric Furoindoline Synthesis by a Flavin-Dependent Monooxygenase Involved in the Biosynthesis of Bicyclic Thiopeptide Thiostrepton. Angew. Chem. Int. Ed. 2021, 60, 8401-8405.
44. Jiang, R.; Ding, L.; Zheng, C.; You, S.-L.* Iridium-catalyzed Z-retentive asymmetric allylic substitution reactions. Science 2021, 371, 380-386.
45. Zhu, M.; Xu, H.; Zhang, X.*; Zheng, C.*; You, S.-L.* Visible-light-induced Intramolecular Double Dearomative Cycloaddition of Arenes. Angew. Chem. Int. Ed. 2021, 60, 7036-7040.
46. Wang, Q.; Liu, C.-X.; Gu, Q.; You, S.-L.* Chiral CpxRh complexes for C–H functionalization reactions. Sci. Bull. 2021, 66, 210-213.
47. Wang, Q.; Zhang, W.-W.; Zheng, C.; Gu, Q.; You, S.-L.* Enantioselective Synthesis of Azoniahelicenes by Rh-Catalyzed C−H Annulation with Alkynes. J. Am. Chem. Soc. 2021, 143, 114-120.
48. Wang, Y.; Zhang, W.-Y.; Xie, J.-H.; Yu, Z.-L.; Tan, J.-H.; Zheng, C.; Hou, X.-L.; You, S.-L.* Enantioselective Desymmetrization of Bisphenol Derivatives via Ir-Catalyzed Allylic Dearomatization. J. Am. Chem. Soc. 2020, 142, 19354-19359.
49. Sharma, U. K.*; Ranjan, P.; Van der Eycken, E. V.*; You, S.-L.* Sequential and Direct Multicomponent Reaction (MCR)-based Dearomatization Strategies. Chem. Soc. Rev. 2020, 49, 8721-8748.
50. Wang, Q.; Zhang, W.-W.; Song, H.; Wang, J.; Zheng, C.; Gu, Q.; You, S.-L.* Rhodium-Catalyzed Atroposelective Oxidative C-H/C-H Cross Coupling Reaction of 1-Aryl Isoquinoline Derivatives with Electron-Rich Heteroarenes. J. Am. Chem. Soc. 2020, 142, 15678-15685.
51. Cheng, Y.-Z.; Huang, X.-L.; Zhuang, W.-H.; Zhao, Q.-R.; Zhang, X.*; Mei, T.-S.*; You, S.-L.* Intermolecular Dearomatization of Naphthalene Derivatives by Photoredox-Catalyzed 1,2-Hydroalkylation. Angew. Chem. Int. Ed. 2020, 59, 18062-18067.
52. Yang, P.; Zheng, C.; Nie, Y.-H.; You, S.-L.* Palladium-Catalyzed Dearomative 1,4-Difunctionalization of Naphthalenes. Chem. Sci. 2020, 11, 6830-6835.
53. Liu, C.-X.; Gu, Q.; You, S.-L.* Asymmetric C-H Bond Functionalization of Ferrocenes: New Opportunities and Challenges. Trends Chem. 2020, 2, 737-749. (Invited submission)
54. Zhu, M.; Huang, X.-L.; Xu, H.; Zhang, X.*; Zheng, C.*; You, S.-L.* Visible-Light-Mediated Synthesis of Cyclobutene-Fused Indolizidines and Related Structural Analogs. CCS Chem. 2020, 2, 652-664.
55. Zheng, C.*; You, S.-L.* Exploring the Chemistry of Spiroindolenines by Mechanistically-Driven Reaction Development: Asymmetric Pictet–Spengler-type Reactions and Beyond. Acc. Chem. Res. 2020, 53, 974-987.
56. Tu, H.-F.; Yang, P.; Lin, Z.-H.; Zheng, C.; You, S.-L.* Time-dependent enantiodivergent synthesis via sequential kinetic resolution. Nature Chem. 2020, 12, 838-844.
57. Cui, W.-J.; Wu, Z.-J.; Gu, Q.; You, S.-L.* Divergent Synthesis of Tunable Cyclopentadienyl Ligands and Their Application in Rh-Catalyzed Enantioselective Synthesis of Isoindolinone. J. Am. Chem. Soc. 2020, 142, 7379-7385.
58. Liu, C.-X.; Cai, Z.-J.; Wang, Q.; Wu, Z.-J.; Gu, Q.; You, S.-L.* Rhodium-Catalyzed Pyridine Assisted C-H Arylation for the Synthesis of Planar Chiral Ferrocenes. CCS Chem. 2020, 2, 642-651.
59. Rossi-Ashton, James A.; Clarke, Aimee K.; Donald, James R.; Zheng, Chao*; Taylor, Richard J. K.*; Unsworth, William P.*; You, Shu-Li* Iridium Catalyzed Enantioselective Intermolecular Indole C2-Allylation. Angew. Chem. Int. Ed. 2020, 59, 7598-7604.
60. Zhang, X.; You, S.-L.* Asymmetric Allylic Substitution Reactions by Ir-Catalysts Derived from C(sp2)-H Activation of Chiral Ligands. Aldrichimica ACTA. 2020, 53, 11-18.
61. Xia, Z.-L.; Xuxu, Q.-F.; Zheng, C.*; You, S.-L.* Chiral phosphoric acid-catalyzed asymmetric dearomatization reactions. Chem. Soc. Rev. 2020, 49, 286-300.
62. Liu, X.-J.; Jin, S.; Zhang, W.-Y.; Liu, Q.-Q.; Zheng, C.; You, S.-L.* Sequence-Dependent Stereodivergent Allylic Alkylation/Fluorination Reaction of Acyclic Ketones. Angew. Chem. Int. Ed. 2020, 59, 2039-2043 (VIP).
63. Cheng, Y.-Z.; Zhao, Q.-R.; Zhang, X.*; You, S.-L.* Asymmetric Dearomatization of Indole Derivatives with N-Hydroxycarbamates Enabled by Photoredox Catalysis. Angew. Chem. Int. Ed. 2019, 58, 18069-18074.
64. Cai, Z.-J.; Liu, C.-X.; Wang, Q.; Gu, Q.*; You, S.-L.* Thioketone-Directed Rhodium(I) Catalyzed Enantioselective C-H Bond Arylation of Ferrocenes. Nat. Commun. 2019, 10, 4168.
65. Xia, Z.-L.; Zheng, C.*; Xu, R.-Q.; You, S.-L.* Chiral Phosphoric Acid Catalyzed Aminative Dearomatization of α-Naphthols/Michael Addition Sequence. Nat. Commun. 2019, 10, 3150.
66. Wang, Q.; Cai, Z.-J.; Liu, C.-X.; Gu, Q.; You, S.-L.* Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls. J. Am. Chem. Soc. 2019, 141, 9504-9510.
67. Liu, X.-J.; Zheng, C.; Yang, Y.-H.; Jin, S.; You, S.-L.* Iridium-Catalyzed Asymmetric Allylic Aromatization Reaction. Angew. Chem. Int. Ed. 2019, 58, 10493-10499.
68. Cheng, Q.; Xie, J.-H.; Weng, Y.-C.; You, S.-L.* Pd-Catalyzed Dearomatization of Anthranils with Vinylcyclopropanes via [4+3] Cyclization Reaction. Angew. Chem. Int. Ed. 2019, 58, 5739-5743 (hot article).
69. Zheng, C.*; You, S.-L.* Catalytic asymmetric dearomatization (CADA) reaction enabled total syntheses of indole-based natural products. Nat. Prod. Rep. 2019, 36, 1589-1605.
70. Wang, Y.; Zhang, W.-Y.; You, S.-L.* Ketones and Aldehydes as O-Nucleophiles in Iridium-Catalyzed Intramolecular Asymmetric Allylic Substitution Reaction. J. Am. Chem. Soc. 2019, 141, 2228-2232.
71. Zhu, M.; Zheng, C.*; Zhang, X.*; You, S.-L.* Synthesis of Cyclobutane-Fused Angular Tetracyclic Spiroindolines via Visible-Light-Promoted Intramolecular Dearomatization of Indole Derivatives. J. Am. Chem. Soc. 2019, 141, 2636-2644.
72. Cai, Z.-J.; Liu, C.-X.; Gu, Q.*; Zheng C.; You, S.-L.* Pd(II)-Catalyzed Regio- and Enantioselective Oxidative C-H/C-H Cross-Coupling Reaction between Ferrocenes and Azoles. Angew. Chem. Int. Ed. 2019, 58, 2149-2153.
73. Xia, Z.-L.; Zheng, C.*; Liang, X.-W.; Cai, Y.; You, S.-L.* Manipulation of Spiroindolenine Intermediates for the Enantioselective Synthesis of 3-(Indol-3-yl)pyrrolidines. Angew. Chem. Int. Ed. 2019, 58, 1158-1162.
74. Cheng, Q.; Hu, H.-F.; Zheng, C.; Qu, J.-P.; Helmchen, G.*; You, S.-L.* Iridium-Catalyzed Asymmetric Allylic Substitution Reactions. Chem. Rev. 2019, 119, 1855-1969.
75. Huang, L.; Cai, Y.; Zhang, H.-J.; Zheng, C.; Dai, L.-X.; You, S.-L.* Chemoselective N-H Functionalization of Indole Derivatives via Reissert-type Reaction Catalyzed by Chiral Phosphoric Acid. CCS Chem. 2019, 1, 106-116.
76. Wang, Q.; Gu, Q.; You, S.-L.* Enantioselective Carbonyl Catalysis Enabled by Chiral Aldehydes. Angew. Chem. Int. Ed. 2019, 58, 6818-6825.
77. Zhang, M.-C.; Wang, D.-C.; Xie, M.-S.; Qu, G.-R.; Guo, H.-M.*; You, S.-L.* Cu-catalyzed Asymmetric Dearomative [3+2] Cycloaddition Reaction of Benzazoles with Aminocyclopropanes. Chem. 2019, 5, 156-167.
78. Yang, Z.-P.; Jiang, R.; Wu, Q.-F.; Huang, L.; Zheng, C.*; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzene Derivatives. Angew. Chem. Int. Ed. 2018, 57, 16190-16193.
79. Xu-Xu, Q.-F.; Liu, Q.-Q.; Zhang, X.*; You, S.-L.* Copper-Catalyzed Ring Opening of Benzofurans and Enantioselective Hydroamination Cascade. Angew. Chem. Int. Ed. 2018, 57, 15204-15208.
80. Tu, H.-F.; Zhang, X.; Zheng, C.; Zhu, M.; You, S.-L.* Enantioselective dearomative prenylation of indole derivatives. Nature Catal. 2018, 1, 601-608. (Tu, H.-F. and Zhang, X. contribute equally)
81. Zheng, C.*; Xia, Z.-L.; You, S.-L.* Unified Mechanistic Understandings of Pictet–Spengler Reactions. Chem. 2018, 4, 1952-1966.
82. Tang, S.-B.; Zhang, X.; Tu, H.-F.; You, S.-L.* Regio- and Enantioselective Rhodium-Catalyzed Allylic Alkylation of Racemic Allylic Alcohols with 1,3-Diketones. J. Am. Chem. Soc. 2018, 140, 7737-7742.
83. Cheng, R.; Li, B.; Wu, J.; Zheng, J.; Qiu, Z.*; Tang, W.; You, S.-L.; Tang, Y.; Xie, Z.* Enantioselective Synthesis of Chiral-at-Cage o-Carboranes via Pd-Catalyzed Asymmetric B−H Substitution. J. Am. Chem. Soc. 2018, 140, 4508-4511.
84. Yang, Z.-P.; Jiang, R.; Zheng, C.*; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Alkylation of Hydroxyquinolines: Simultaneous Weakening the Aromaticity of Two Consecutive Aromatic Rings. J. Am. Chem. Soc. 2018, 140, 3114-3119.
85. Xia, Z.-L.; Zheng, C.*; Wang, S.-G.; You, S.-L.* Catalytic Asymmetric Dearomatization of Indolyl Dihydropyridines via Enamine Isomerization/Spirocyclization/Transfer Hydrogenation Sequence. Angew. Chem. Int. Ed. 2018, 57, 2653-2656.
86. Cheng, Q.; Zhang, F. Cai, Y.; Guo, Y.-L.*; You, S.-L.* Stereodivergent Synthesis of Tetrahydrofuroindoles via Pd-Catalyzed Asymmetric Dearomative Formal [3+2] Cycloaddition Reactions. Angew. Chem. Int. Ed. 2018, 57, 2134-2138.
87. Cai, Z.-J.; Liu, C.-X.; Gu, Q.; You, S.-L.* Thioketone Directed Palladium(II)-Catalyzed C-H Arylation of Ferrocenes with Aryl Boronic Acids. Angew. Chem. Int. Ed. 2018, 57, 1296-1299.
88. Zhang, X.; You, S.-L.* Removing the Mask in Catalytic Asymmetric Diamination of Alkenes. Chem. 2017, 2, 917-929.
89. Wang, Y.; Zheng, C.*; You, S.-L.* Ir-Catalyzed Asymmetric Allylic Dearomatization via a Desymmetrization Strategy. Angew. Chem. Int. Ed. 2017, 56, 15093-15097. (VIP)
90. Huang, L.; Cai, Y.; Zheng, C.; Dai, L.-X.; You, S.-L.* Iridium-Catalyzed Enantioselective Synthesis of Pyrrole-Annulated Medium-Sized-Ring Compounds. Angew. Chem. Int. Ed. 2017, 56, 10545-10548.
91. Cheng, Q.; Zhang, H.-J.; Yue, W.-J.; You, S.-L.* Palladium-Catalyzed Highly Stereoselective Dearomative [3+2] Cycloaddition of Nitrobenzofurans. Chem. 2017, 2, 428-436.
92. Wang, S.-G.; Xia, Z.-L.; Xu, R.-Q.; Liu, X.-J.; Zheng, C.; You, S.-L.* Construction of Chiral Tetrahydro-β-Carbolines through Asymmetric Pictet-Spengler Reaction of Indolyl Dihydropyridines. Angew. Chem. Int. Ed. 2017, 56, 7440-7443. (Wang, S.-G. and Xia, Z.-L. contribute equally)
93. Xu, R.-Q.; Gu, Q.; You, S.-L.* Construction of Benzomesembrine Skeleton via Pd(0)-Catalyzed Intermolecular Arylative Dearomatization of α-Naphthols and Aza-Michael Cascade. Angew. Chem. Int. Ed. 2017, 56, 7252-7256.
94. Zheng, J.; Wang, S.-B.; Zheng, C.; You, S.-L.* Asymmetric Synthesis of Spiropyrazolones via Rh-Catalyzed C(sp2)−H Functionalization/Annulation Reactions. Angew. Chem. Int. Ed. 2017, 56, 4540-4544.
95. Liu, X.-J.; You, S.-L.* Enantioselective Iridium-Catalyzed Allylic Substitution with 2-Methylpyridines. Angew. Chem. Int. Ed. 2017, 56, 4002-4005.
96. Gao, D.-W.; Gu, Q.; Zheng, C.; You, S.-L.* Synthesis of Planar Chiral Ferrocenes via Transition-Metal-Catalyzed Direct C–H Bond Functionalization. Acc. Chem. Res. 2017, 50, 351-365.
97. Tu, H.-F.; Zheng, C.; Xu, R.-Q.; Liu, X.-J.; You, S.-L.* Ir-Catalyzed Intermolecular Asymmetric Dearomatization of β-Naphthols with Allyl Alcohols or Allyl Ethers. Angew. Chem. Int. Ed. 2017, 56, 3237-3241. (VIP)
98. Yang, Z.-P.; Zheng, C.; Huang, L.; Qian, C.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Benzoxazoles, Benzothiazoles and Benzimidazoles. Angew. Chem. Int. Ed. 2017, 56, 1530-1534.
99. Zheng, C.; You, S.-L.* Catalytic Asymmetric Dearomatization (CADA) by Transition-metal-catalysis: A Method for Transformations of Aromatic Compounds. Chem. 2016, 1, 830-857.
100. Xu, R.-Q.; Yang, P.; Tu, H.-F.; Wang, S.-G.; You, S.-L.* Palladium(0)-Catalyzed Intermolecular Arylative Dearomatization of β-Naphthols. Angew. Chem. Int. Ed. 2016, 55, 15137-15141.
101. Wang, D.-C.; Xie, M.-S.; Guo, H.-M.*; Qu, G.-R.; Zhang, M.-C.; You, S.-L.* Enantioselective Dearomative [3+2] Cycloaddition Reactions of Benzothiazoles. Angew. Chem. Int. Ed. 2016, 55, 14111-14115.
102. Huang, L.; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of Indole-Annulated Medium-Sized Rings. J. Am. Chem. Soc. 2016, 138, 5793-5796.
103. Ye, K.-Y.; Cheng, Q.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L.* Iridium(I) N-Heterocyclic Carbene Complex Catalyzed Asymmetric Intramolecular Allylic Amination Reactions. Angew. Chem. Int. Ed. 2016, 55, 8113-8116.
104. Zheng, J.; Cui, W.-J.; Zheng, C.; You, S.-L.* Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes. J. Am. Chem. Soc. 2016, 138, 5242-5245.
105. Wu, Q.-F.; Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Highly Efficient Synthesis and Stereoselective Migration Reactions of Chiral Five-Membered Aza-Spiroindolenines: Scope and Mechanistic Understanding. Chem. Sci. 2016, 7, 4453-4459.
106. Gao, D.-W.; Gu, Q.; You, S.-L.* An Enantioselective Oxidative C–H/C–H Cross-Coupling Reaction: Highly Efficient Method to Prepare Planar Chiral Ferrocenes. J. Am. Chem. Soc. 2016, 138, 2544-2547.
107. Cheng, Q.; Wang, Y.; You, S.-L.* Chemo-, Diastereo- and Enantioselective Ir-Catalyzed Allylic Intramolecular Dearomatization Reaction of Naphthol Derivatives. Angew. Chem. Int. Ed. 2016, 55, 3496-3499.
108. Wu, W.-T.; Xu, R.-Q.; Zhang, L.*; You, S.-L.* Construction of Spirocarbocycles via Gold-Catalyzed Intramolecular Dearomatization of Naphthols. Chem. Sci. 2016, 7, 3427-3431.
109. Wu, W.-T.; Zhang, L.*; You, S.-L.* Catalytic Asymmetric Dearomatization (CADA) Reactions of Phenol and Aniline Derivatives Chem. Soc. Rev. 2016, 45, 1570-1580.
110. Liu, C.; Yi, J.-C.; Zheng, Z.-B.; Tang, Y.*; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of 3a-Amino-pyrroloindolines via Copper-Catalyzed Direct Asymmetric Dearomative Amination of Tryptamines. Angew. Chem. Int. Ed. 2016, 55, 751-754.
111. Yang, Z.-P.; Wu, Q.-F.; Shao, W.; You, S.-L.* Iridium-Catalyzed Intramolecular Asymmetric Allylic Dearomatization Reaction of Pyridines, Pyrazines, Quinolines and Isoquinolines. J. Am. Chem. Soc. 2015, 137, 15899-15906.
112. Wang, S.-G.; Liu, X.-J.; Zhao, Q.-C.; Zheng, C.; Wang, S.-B.; You, S.-L.* Asymmetric Dearomatization of β-Naphthols through a Bifunctional-Thiourea-Catalyzed Michael Reaction. Angew. Chem. Int. Ed. 2015, 54, 14929-14932.
113. Zhuo, C.-X.; Zhou, Y.; Cheng, Q.; Huang, L.; You, S.-L.* Enantioselective Construction of Spiroindolines with Three Contiguous Stereogenic Centers and Chiral Tryptamine Derivatives: Reactive Spiroindolenine Intermediates. Angew. Chem. Int. Ed. 2015, 54, 14146-14149.
114. Zhang, X.; Liu, W.-B.; Tu, H.-F.; You, S.-L.* Ligand-Enabled Ir-Catalyzed Intermolecular Diastereoselective and Enantioselective Allylic Alkylation of 3-Substituted Indoles. Chem. Sci. 2015, 6, 4525-4529.
115. Zhuo, C.-X.; Cheng, Q.; Liu, W.-B.; Zhao, Q.; You, S.-L.* Enantioselective Synthesis of Pyrrole Based Spiro- and Polycyclic Derivatives by Ir-catalyzed Asymmetric Allylic Dearomatization and Controllable Migration Reactions. Angew. Chem. Int. Ed. 2015, 54, 8475-8479.
116. Li, G.-T.; Gu, Q.; You, S.-L.* Enantioselective Annulation of Enals with 2-Naphthols by Triazolium Salts Derived from L-Phenylalanine. Chem. Sci. 2015, 6, 4273-4278.
117. Yin, Q.; Wang, S.-G.; Liang, X.-W.; Gao, D.-W.; Zheng, J.; You, S.-L.* Organocatalytic Asymmetric Chlorinative Dearomatization of Naphthols. Chem. Sci. 2015, 6, 4179-4183.
118. Shao, W.; Li, H.; Liu, C.; Liu, C.-J.*; You, S.-L.* Copper-Catalyzed Intermolecular Asymmetric Propargylic Dearomatization of Indoles. Angew. Chem. Int. Ed. 2015, 54, 7684-7687.
119. Zheng, J.; Wang, S.-B.; Zheng, C.; You, S.-L.* Asymmetric Dearomatization of Naphthols via a Rh-Catalyzed C(sp2)–H Functionalization/Annulation Reaction. J. Am. Chem. Soc. 2015, 137, 4880-4883.
120. Zhang, X.; Yang, Z.-P.; Huang, L.; You, S.-L.* Highly Regio- and Enantioselective Synthesis of N-Substituted 2-pyridones via Ir-Catalyzed Intermolecular Asymmetric Allylic Amination. Angew. Chem. Int. Ed. 2015, 54, 1873-1876.
121. Wang, S.-G.; Yin, Q.; Zhuo, C.-X.; You, S.-L.* Asymmetric Dearomatization of β-Naphthols via Chiral Phosphoric Acid-Catalyzed Amination Reaction. Angew. Chem. Int. Ed. 2015, 54, 647-650.
122. Zheng, C.*; Zhuo, C.-X.; You, S.-L.* Mechanistic Insights into the Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Multisubstituted Pyrroles: Understanding the Remarkable Regio- and Enantioselectivity. J. Am. Chem. Soc. 2014, 136, 16251-16259.
123. Xu, R.-Q.; Gu, Q.; Wu, W.-T.; Zhao, Z.-A.; You, S.-L.* Construction of Erythrinane Skeleton via Pd(0)-Catalyzed Intramolecular Dearomatization of para-Aminophenols J. Am. Chem. Soc. 2014, 136, 15469-15472.
124. Zheng, J.; You, S.-L.* Construction of Axial Chirality via Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes. Angew. Chem. Int. Ed. 2014, 53, 13244-13247.
125. Zhuo, C.-X.; Zheng, C.; You, S.-L.* Transition-metal-catalyzed Asymmetric Allylic Dearomatization Reactions Acc. Chem. Res. 2014, 47, 2558-2573.
126. Yang, Z.-P.; Wu, Q.-F.; You, S.-L.* Direct Asymmetric Dearomatization of Pyridines and Pyrazines via Ir-Catalyzed Allylic Amination Reactions. Angew. Chem. Int. Ed. 2014, 53, 6986-6989.
127. Zhuo, C.-X.; Zhou, Y.; You, S.-L.* Highly Regio- and Enantioselective Synthesis of Poly-Substituted 2H-Pyrroles via Pd-Catalyzed Intermolecular Asymmetric Allylic Dearomatization of Pyrroles J. Am. Chem. Soc. 2014, 136, 6590-6593 (selected as JACS Spotlights).
128. Gao, D.-W.; Yin, Q.; Gu, Q.*; You, S.-L.* Enantioselective Synthesis of Planar Chiral Ferrocenes via Pd(0)-Catalyzed Intramolecular Direct C-H Bond Arylation J. Am. Chem. Soc. 2014, 136, 4841-4844.
129. Li, W.; Liu, C.; Zhang, H.; Ye, K.; Zhang, G.; Zhang, W.; Duan, Z.; You, S.*; Lei, A.* Palladium-Catalyzed Oxidative C-H/N-H Carbonylation for the Synthesis of β-lactams. Angew. Chem. Int. Ed. 2014, 53, 2443-2446.
130. Wang, S.-G.; You, S.-L.* Cascade Hydrogenative Dearomatization of Pyridine and Asymmetric aza-Friedel-Crafts Alkylation Reaction. Angew. Chem. Int. Ed. 2014, 53, 2194-2197.
131. Zhang, X.; Han, L.; You, S.-L.* Ir-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Indoles. Chem. Sci. 2014, 5, 1059-1063.
132. Zhuo, C.-X.; You, S.-L.* Palladium-Catalyzed Intermolecular Asymmetric Allylic Dearomatization Reaction of Naphthol Derivatives. Angew. Chem. Int. Ed. 2013, 52, 10056-10059.
133. Zhang, X.; Yang, Z.-P.; Liu, C.; You, S.-L.* Ru-Catalyzed Intermolecular Dearomatization Reaction of Indoles with Allylic Alcohols. Chem. Sci. 2013, 4, 3239-3243.
134. Zhuo, C.-X.; Wu, Q.-F.; Zhao, Q.; Xu, Q.-L.; You, S.-L.* Enantioselective Functionalization of Indoles and Pyrroles via An in-situ Formed Spiro-intermediate J. Am. Chem. Soc. 2013, 135, 8169-8172.
135. Gao, D.-W.; Shi, Y.-C.; Gu, Q.*; Zhao, Z.-L.; You, S.-L.* Enantioselective Synthesis of Planar Chiral Ferrocenes via Palladium-catalyzed Direct Coupling with Aryl Boronic Acids J. Am. Chem. Soc. 2013, 135, 86-89.
136. Xu, Q.-L.; Dai, L.-X.; You, S.-L.* Diversity Oriented Synthesis of Indole-based Peri-annulated Compounds via Allylic Alkylation Reactions. Chem. Sci. 2013, 4, 97-102.
137. Zhuo, C.-X.; Zhang, W.*; You, S.-L.* Catalytic Asymmetric Dearomatization Reactions. Angew. Chem. Int. Ed. 2012, 51, 12662-12686.
138. Liu, W.-B.; Zhang, X.; Dai, L.-X.; You, S.-L.* Asymmetric N-Allylation of Indoles via Ir-Catalyzed Allylic Alkylation of Indolines and Oxidation Strategy. Angew. Chem. Int. Ed. 2012, 51, 5183-5187.
139. Liu, W.-B.; Zheng, C.; Zhuo, C.-X.; Dai, L.-X.; You, S.-L.* Ir-Catalyzed Allylic Alkylation Reaction with N-Aryl Phosphoramidite Ligands: Scope and Mechanistic Studies J. Am. Chem. Soc. 2012, 134, 4812-4821.
140. Zheng, C.; You, S.-L.* Transfer Hydrogenation with Hantzsch Esters and Related Organic Hydride Donors Chem. Soc. Rev. 2012, 41, 2498-2518. (invited paper)
141. Wu, Q.-F.; Zheng, C.; You, S.-L.* Enantioselective Syntheses of Spiro Cyclopentane-1,3'-indoles and 2,3,4,9-Tetrahydro-1H-carbazoles via Ir-Catalyzed Allylic Dearomatization and Stereospecific Migration. Angew. Chem. Int. Ed. 2012, 51, 1680-1683.
142. Zhuo, C.-X.; Liu, W.-B.; Wu, Q.-F.; You, S.-L.* Asymmetric Dearomatization of Pyrroles via Ir-Catalyzed Allylic Substitution Reaction: Enantioselective Synthesis of Spiro-2H-pyrroles. Chem. Sci. 2012, 3, 205-208.
143. Ye, K.-Y.; He, H.; Liu, W.-B.; Helmchen, G.; Dai, L-X.; You, S.-L.* Iridium-Catalyzed Allylic Vinylation and Asymmetric Allylic Amination Reactions with ortho-Aminostyrenes J. Am. Chem. Soc. 2011, 133, 19006-19014.
144. Cai, Q.; Zheng, C.; Zhang, J.-W.; You, S.-L.* Enantioselective Michael-Mannich Polycyclization Cascade of Indolyl Enones by Quinine-Derived Primary Amine Angew. Chem. Int. Ed. 2011, 50, 8665-8669.
145. Gu, Q.; You, S.-L.* Desymmetrization of Cyclohexadienones via Cinchonine Derived Thiourea-Catalyzed Enantioselective Aza-Michael Reaction and Total Synthesis of (-)-Mesembrine. Chem. Sci. 2011, 2, 1519-1522.
146. Yin, Q.; You, S.-L.* Chiral Phosphoric Acid-Catalysed Friedel-Crafts Alkylation Reaction of Indoles with Racemic Spiro Indolin-3-ones. Chem. Sci. 2011, 2, 1344-1348.
147. Wu, Q.-F.; Liu, W.-B.; Zhuo, C.-X.; Rong, Z.-Q.; Ye, K.-Y.; You, S.-L.* Ir-Catalyzed Intramolecular Asymmetric Allylic Dearomatization of Phenols. Angew. Chem. Int. Ed. 2011, 50, 4455-4458.
148. Cai, Q.; Zheng, C.; You, S.-L.* Enantioselective Intramolecular Aza-Michael Addition of Indoles Catalyzed by Chiral Phosphoric Acid. Angew. Chem. Int. Ed. 2010, 49, 8666-8669.
149. Wu, Q.-F.; He, H.; Liu, W.-B.; You, S.-L.* Enantioselective Construction of Spiroindolenines by Ir-Catalyzed Allylic Alkylation Reactions J. Am. Chem. Soc. 2010, 132, 11418-11419.
150. Peng, H. M.; Dai, L.-X.; You, S.-L.* Enantioselective Palladium-Catalyzed Direct Alkylation and Olefination Reaction of Simple Arenes Angew. Chem. Int. Ed. 2010, 49, 5826-5828. (Highlights)
151. Gu, Q.; Rong, Z.-Q.; Zheng, C.; You, S.-L.* Desymmetrization of Cyclohexadienones via Brønsted Acid-Catalyzed Enantioselective Oxo-Michael Reaction J. Am. Chem. Soc. 2010, 132, 4056-4057.
152. He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L.* Enantioselective Synthesis of 2,3-Dihydro-1H-benzo[b]azepines via Ir-Catalyzed Tandem Allylic Vinylation/Amination Reaction. Angew. Chem. Int. Ed. 2010, 49, 1496-1499.
153. Cai, Q.; Zhao, Z.-A.; You, S.-L.* Asymmetric Construction of Polycyclic Indoles through Olefin Cross-Metathesis/ Intramolecular Friedel-Crafts Alkylation under Sequential Catalysis. Angew. Chem. Int. Ed. 2009, 48, 7428-7431.
154. He, H.; Liu, W.-B.; Dai, L.-X.; You, S.-L.* Ir-Catalyzed Cross-Coupling of Styrene Derivatives with Allylic Carbonates: Free Amine Assisted Vinyl C-H Bond Activation J. Am. Chem. Soc. 2009, 131, 8346-8347.
155. You, S.-L.*; Cai, Q.; Zeng, M. Chiral Brønsted Acids Catalyzed Friedel-Crafts Alkylation Reaction Chem. Soc. Rev. 2009, 38, 2190-2201.
156. Kang, Q.; Zhao, Z.-A.; You, S.-L.* Highly Enantioselective Friedel-Crafts Reaction of Indoles with Imines by a Chiral Phosphoric Acid. J. Am. Chem. Soc. 2007, 129, 1484-1485.
157. You, S.-L.*; Dai, L.-X. Enantioselective Palladium-Catalyzed Decarboxylative Allylic Alkylations. Angew. Chem. Int. Ed. 2006, 45, 5246-5248.
