质谱技术开发与代谢组学应用研究

1. Cai Y, X. Chen, F. Ren, H. Wang, Y. Yan, and Z.-J. Zhu*, Fast and broad-coverage lipidomics enabled by ion mobility-mass spectrometry. Analyst, 2024, 149, 5063-5072.

2. J. Lv^#, C. Pan^#, Cai Y^#, X. Han, C. Wang, J. Ma, J. Pang, F. Xu, S. Wu, T. Kou, F. Ren, Z.-J. Zhu*, T. Zhang*, J. Wang* and Y. Chen*, Plasma metabolomics reveals the shared and distinct metabolic disturbances associated with cardiovascular events in coronary artery disease. Nature Communications, 2024, 15: 5729. 

3. B. Yin^#, Cai Y^#, T. Teng^#, X. Wang, X. Liu, X. Li, Jie Wang, H. Wu, Y. He, F. Ren, T. Kou, Z.-J. Zhu* and X. Zhou* , Identifying plasma metabolic characteristics of major depressive disorder, bipolar disorder, and schizophrenia in adolescents. Translational Psychiatry, 2024, 14: 163.   

4. Cai Y, Zhou Z., and Zhu Z.-J*, Advanced Analytical and Informatic Strategies for Metabolite Annotation in Untargeted Metabolomics. TrAC Trends in Anal. Chem., 2023, 158:116903.

5. H. Wang^#, H. Jia^#, Y. Gao, H. Zhang, J. Fan, L. Zhang, F. Ren, Y. Yin, Cai Y*, J. Zhu*, and Zhu Z.-J*, Serum Metabolic Traits Reveal Therapeutic Toxicities and Responses of Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer, Nature Communications, 2022, 13: 7802. 

6. Liu W, Zhang W*, Li T, Zhou Z, Luo M, Chen X, Cai Y*, and Zhu Z.-J*.Four-dimensional Untargeted Profiling of N-acylethamolamine Lipids in the Mouse Brain Using Ion Mobility-Mass Spectrometry. Analytical Chemistry, https://doi.org/10.1021/acs.analchem.2c02650, 2022

7. Chen X, Yin Y, Luo M, Zhou Z, Cai Y*, and Zhu Z.-J*.Trapped Ion Mobility Spectrometry-Mass Spectrometry Improves the Coverage and Accuracy of Four-dimensional Untargeted Lipidomics. Analytica Chimica Acta, 1210:339886, 2022

8. Li T, Yin Y, Zhou Z, J. Qiu, W. Liu, X. Zhang, K. He, Cai Y, and Zhu Z.-J*, Ion Mobility-based Sterolomics Reveals Spatially and Temporally Distinctive Sterol Lipids in the Mouse Brain, Nature Communications, 12: 4343, 2021 

9. Cai Y, Kim D, Takahashi T, Broadhurst DI, Ma S, Rattray Z, Casanovas A, Yale IMPACT Research Team, Ko AI, Khan S, Iwasaki A, Johnson CH. Kynurenic Acid Underlies Sex-specific Immune Responses to COVID-19. Science Signaling, 14 (690), eab8483, 2021

10.  Cai Y, Vollmar AK, Johnson CH. Analyzing metabolomics data for environmental health and exposome, Computational Methods and Data Analysis for Metabolomics. Methods in Molecular Biology (2019).

11. Cai Y, Zhu Z.-J. A High-Throughput Targeted Metabolomics Workflow for the Detection of 200 Polar Metabolites in Central Carbon Metabolism, Methods in Molecular Biology, 2019, 1859, 263-274.

12. Cai Y, N. Liu, Zhu Z.-J, Stable-isotope Labeled Metabolic Analysis in Drosophila melanogaster: From Experimental Setup to Data Analysis, Bio-protocol, 2018, 8(18): e3015.

13. Ma J^#, Wang H^#, Cai Y^#, Wang H^#, Kong Y, Wu F, Ma H, Yang Y, Zhang Y, Zhu Z.-J, Liu N. Epigenetic Drift of H3K27me3 Links Glycolysis to Healthy Longevity, eLife, 2018,7: e35368.

14. Zha H^#, Cai Y^#, Yin Y^#, Wang Z, Li K, Zhu Z.-J. SWATHtoMRM: Development of High-Coverage Targeted Metabolomics Method with Using SWATH-MS technology for Biomarker Discovery, Analytical Chemistry, 2018, 90, 4062-4070.