基于主族元素配体偶联机理的新型氟化学反应研究
基于过渡金属参与机理的新型氟化学反应研究
具有应用目标导向的新型氟化和氟烷基化技术的开发
13. Prakash, G. K. Surya*; Wang, Fang; Rahm, Martin; Shen, Jingguo; Ni, Chuanfa; Haiges, Ralf; Olah, George A.*, “On the Nature of C-H...F-C Interactions in Hindered CF3-C(sp3) Bond Rotations”, Angew. Chem. Int. Ed. 2011, 50, 11761–11764.
12. Prakash, G. K. Surya*; Wang, Fang; Ni, Chuanfa; Shen, Jingguo; Haiges, Ralf; Yudin, Andrei K.; Mathew, Thomas; Olah, George A.*, “Conformational Study of 9-Dehydro-9-Trifluoromethyl Cinchona Alkaloids via 19F NMR Spectroscopy: Emergence of Trifluoromethyl Moiety as a Conformational Stabilizer and a Probe”, J. Am. Chem. Soc. 2011, 133, 9992 –9995.
11. Prakash, G. K. Surya*; Ni, Chuanfa; Wang, Fang; Hu, Jinbo; Olah, George A.*, “From Difluoromethyl 2-Pyridyl Sulfone to Difluorinated Sulfonates: A Unique Protocol for Nucleophilic Difluoro(sulfonato)methylation”, Angew. Chem. Int. Ed. 2011, 50, 2559–2563. (Highlighted by Synfacts)
10. Ni, Chuanfa; Hu, Jinbo*, “Selective Nucleophilic Fluoroalkylations Facilitated by Removable Activation Groups”, Synlett, 2011, 770-782. (An Invited Account)
9. Prakash, G. K. Surya*; Wang, Fang; Ni, Chuanfa; Thomas, Tito Joe; Olah, George A.*, “Efficient Synthesis of α-(Fluoro/chloro/methoxy)disulfonylmethane Derivatives as Tunable Substituted Methyl Synthons via a New C-S Bond Forming Strategy”, J. Fluorine Chem. 2010, 131, 1007–1012.
8. Ni, Chuanfa; Zhang Laijun; Hu, Jinbo*, “Synthesis of Fluorinated β-Ketosulfones and gem-Disulfones by Nucleophilic Fluoroalkylation of Esters and Sufinates with Di- and Monofluoromethyl Sulfones”, J. Org. Chem. 2009, 74, 3767–3771.
7. Ni, Chuanfa; Hu, Jinbo*, “Palladium/acetic acid-catalyzed fluoroalkylation of alkynes with monofluorinated sulfones as pronucleophiles”, Tetrahedron Lett. 2009, 50, 7252–7255.
6.Ni, Chuanfa; Zhang Laijun; Hu, Jinbo*, “Nucleophilic Fluoroalkylation of α,β-Enones, Arynes and Activated Alkynes with Fluorinated Sulfones: Probing the Hard/Soft Nature of Fluorinated Carbanions”, J. Org. Chem. 2008, 73, 5699–5713.
5.Ni, Chuanfa; Wang Fang; Hu, Jinbo*, “Enantioselective nucleophilic difluoromethylation of aromatic aldehydes With Me3SiCF2SO2Ph and PhSO2CF2H reagents catalysed by chiral quaternary ammonium salts”, Beilstein J. Org. Chem. 2008, 4, No. 21.
4. Ni, Chuanfa; Liu, Jun; Zhang, Laijun; Hu, Jinbo*, “A Remarkably Efficient Fluoroalkylation of Cyclic Sulfates and Sulfamidates with PhSO2CF2H: Facile Entry into β-Difluoromethylated or β-Difluoromethylenated Alcohols and Amines”, Angew. Chem., Int. Ed. 2007, 46, 786–789.
3. Ni, Chuanfa; Li, Ya; Hu, Jinbo*, “Nucleophilic Fluoroalkylation of Epoxides with Fluorinated Sulfones”, J. Org. Chem. 2006, 71, 6829–6833.
2. Li, Ya; Ni, Chuanfa; Liu, Jun; Zhang, Laijun; Zheng, Ji; Zhu, Lingui; Hu, Jinbo*, “Stereoselective Nucleophilic Monofluoromethylation of N-(tert-Butanesulfinyl)imines with Fluoromethyl Phenyl Sulfone”, Org. Lett. 2006, 8, 1693–1696.
1. Ni, Chuanfa; Hu, Jinbo*, “Nucleophilic difluoromethylation of carbonyl compounds using TMSCF2SO2Ph and Mg0-mediated desulfonylation”, Tetrahedron Lett. 2005, 46, 8273–8277.
申请专利:
胡金波, 倪传法 [(苯磺酰)二氟甲基]三甲基硅烷的制备方法, 中国专利, 专利号:ZL2005 1 0027760.2
胡金波, 倪传法 [(苯磺酰)二氟甲基]三甲基硅烷参与的对羰基化合物的二氟甲基化反应, 中国专利, 专利号:ZL 2005 1 0027758.5