副研究员
王昊阳
职  称: 高级工程师
学  历: 研究生
电  话: 021-54925307
职  务:
传  真: 021-64166128
电子邮件: haoyangwang@mail.sioc.ac.cn
个人网页:
通信地址: 上海市零陵路345号
个人简历

1996/09–2000/06,中国药科大学,药学院,药物分析专业,本科

2000/09–2003/06,中国药科大学与上海有机化学研究所联合培养,硕士

2003/09–2006/06,中国科学院上海有机化学研究所,博士

2006/07–2008/07,德国奥尔登堡大学,化学系,博士后

2008/09–2017/02,中国科学院上海有机化学研究所,副研究员

2017/03–至今,中国科学院上海有机化学研究所,公共技术服务中心质谱组,课题组长

研究方向

主要从事有机质谱学研究,致力于开发和设计新质谱学新技术解决有机化学中有挑战的难题,并基于有机化学基本理论发展新的质谱学方法。在新型质谱离子源研发,反应机理与气相化学研究,食品安全和药物分析的质谱快检技术开发等方面取得了一些科研成果。

 

社会任职
获奖及荣誉
代表论著

1.         Meng-Xi Wu, Hao-Yang Wang*, Jun-Ting Zhang, Yin-Long Guo*. Multifunctional Carbon Fiber Ionization Mass Spectrometry, Anal. Chem. 2016, 88(19), 9547?9553.

2.         Jun-Ting Zhang, Hao-Yang Wang*, Xiang Zhang, Fang Zhang, Yin-Long Guo*. Study of short-lived and early reaction intermediates in organocatalytic asymmetric amination reactions by ion-mobility mass spectrometry. Catal. Sci. Technol. 2016, 6, 6637–6643.

3.         Qilun Liu, Zheliang Yuan, Hao-Yang Wang*, Yang Li, Yichen Wu, Tao Xu, Xuebing Leng, Pinhong Chen, Yin-long Guo, Zhenyang Lin*, Guosheng Liu*. Abnormal Mesoionic Carbene Silver Complex: Synthesis, Reactivity and Mechanistic Insight on Oxidative Fluorination. ACS Catalysis, 2015, 5(11), 6732–6737.

4.         Zheliang Yuan, Hao-Yang Wang, Xin Mu, Pinhong Chen, Yin-long Guo, Guosheng Liu*. Highly Selective Pd-Catalyzed Intermolecular Fluorosulfonylation of Styrenes. J. Am. Chem. Soc. 2015, 137(7), 2468–2471.

5.         Xiao-Pan Liu, Hao-Yang Wang*, Jun-Ting Zhang, Meng-Xi Wu, Wan-Shu Qi, Hui Zhu, Yin-Long Guo*. Direct and Convenient Mass Spectrometry Sampling with Ambient Flame Ionization. Scientific Reports, 2015, 5, 16893.

6.         Hao-Yang Wang*, Jun-Ting Zhang, Shu-Sheng Zhang, Yin-Long Guo*. The remarkable role of solvent in reaction mechanism studies by electrospray mass spectrometry. Org. Chem. Front., 2015, 2, 990–994.

7.         Hao-Yang Wang*, Jun-Ting Zhang, Shi-Hao Sun, Shu-Sheng Zhang, Fang Zhang, Hui Zhu, Yin-Long Guo*. Study on the Accelerated Gutknecht Self-Cyclocondensation of Amino-sugars at Atmospheric Pressure Chemical Ionization Condition. RSC Advances, 2015, 5, 105079–105083.

8.         Youai Qiu, Jing Zhou, Junzhao Li, Chunling Fu, Yin-long Guo, Haoyang Wang*, Shengming Ma*. Asymmetric Construction of Six-Membered Rings by Cyclization of Allenes with Dinuclear Gold Catalysis. Chem. Eur. J. 2015, 21(45):15939–15943.

9.         Jun-Ting Zhang, Hao-Yang Wang*, Wei Zhu, Ting-Ting Cai, Yin-Long Guo*. Solvent-assisted Electrospray Ionization for Direct Analysis of Various Compounds (complex) from Low/non-polar Solvents and Eluents. Anal. Chem. 2014, 86(18), 8937–8942.

10.     Haoyang Wang*, Zhixiong Zhao, Yinlong Guo*. Chemical and biochemical applications of MALDI TOF-MS based on analyzing the small organic compounds. in: Applications of MALDI-TOF Spectroscopy. Zongwei Cai, Shuying Liu (Eds.) Top. Curr. Chem. 2013, 331, 165–192.

11.     Hao-Yang Wang*, Ying Gao, Fang Zhang, Chong-Tian Yu, Chu Xu, Yin-Long Guo*. Mass spectrometric study of the gas-phase difluorocarbene expulsion of polyfluorophenyl cations via F-atom migration. J. Am. Soc. Mass Spectrom. 2013, 24(12), 19191926.

12.     Hao-Yang Wang*, Zhang Xiang, Guo-Sheng Liu, Yin-Long Guo*. Study of the gas phase intramolecular aryltrifluoromethylation of phenyl(trifluoromethyl) iodonium by ESI-MS/MS. J. Am. Soc. Mass Spectrom. 2013, 24(5), 761–767.

13.     Hao-Yang Wang, Wai-Leung Yim, Yin-Long Guo, Jürgen O. Metzger*. ESI-MS studies and calculations on second-generation Grubbs and Hoveyda-Grubbs ruthenium olefin metathesis catalysts. Organometallics 2012, 31(5), 1627–1634.

14.     Xin Mu, Tao Wu, Hao-yang Wang, Yin-long Guo, Guosheng Liu*. Palladium-catalyzed oxidative aryltrifluoromethylation of activated alkenes at room temperature. J. Am. Chem. Soc. 2012, 134 (2), 878–881.

15.     Hao-Yang Wang, Wai-Leung Yim, Thorsten Klüner, Jürgen O. Metzger*. ESIMS studies and calculations on alkali metal adduct ions of Ruthenium olefin metathesis catalysts and their catalytic activity in metathesis reactions. Chem. Eur. J. 2009, 15(41), 10948-10959.

16.     Cesar A. Marquez, Haoyang Wang, Francesco Fabbretti, Ju?rgen O. Metzger*. Electron-transfer-catalyzed dimerization of trans-anethole: detection of the distonic tetramethylene radical cation intermediate by extractive electrospray ionization mass spectrometry. J. Am. Chem. Soc. 2008, 130(51), 17208-17209.

17.     Haoyang Wang, Jürgen O. Metzger*. ESI-MS Study on first generation Ruthenium olefin metathesis catalysts in solution: direct detection of the catalytically active 14-electron ruthenium intermediate. Organometallics. 2008, 27(12), 2761-2766.

18.     Hao-Yang Wang, Qing Hong Tang, Xiang Zhang, Yin-Long Guo*, Long Lu*. Using tandem mass spectrometry to predict chemical transformations of 2-pyrimidinyloxy-N-arylbenzyl amine derivatives in solution. J. Am. Soc. Mass Spectrom. 2006, 17(2), 253-263.

19.     Hao-Yang Wang, Xiang Zhang, Yin-Long Guo*, Long Lu*. Mass spectrometric studies of the gas phase retro-Michael type fragmentation reactions of 2-hydroxybenzyl-N-Pyrimidinylamine derivatives. J. Am. Soc. Mass Spectrom. 2005, 16(10), 1561-1573.

20.     Hao-Yang Wang, Yin-Long Guo*, Long Lu*. Studies of rearrangement reactions of protonated and lithium cationized 2-pyrimidinyloxy-N-arylbenzylamine derivatives by MALDI-FTICR MS. J. Am. Soc. Mass Spectrom. 2004, 15(12), 1820-1832.

承担科研项目情况