2013 南开大学优秀博士毕业生

2021 国家优秀青年科学基金 (结题评估为“优”)

[1] “Computational analysis of modular diazotransfer reactions for the development of predictive-reactivity models and diazotransfer reagents” Meng-Meng Zheng^#, Liu Cai^#, Tiancheng Ma, Hao-Dong Tan, Xiaoyu Lai, Jiajia Dong*, Xiao-Song Xue*, Nat. Synth. 2024, 3, 1507–1517. (Research Briefing: 10.1038/s44160-024-00634-1).

[2] “C(sp3)-F Bond Activation by Lewis Base-Boryl Radicals via Concerted Electron-Fluoride Transfer” Xueying Guo^#, Yuchen Zhang^#, Xiaoyu Lai, Yubing Pang, Xiao-Song Xue*, Angew. Chem. Int. Ed. 2024, e202415715. 

[3] “Rhodium-Catalyzed Asymmetric Reductive Hydroformylation of α-Substituted Enamides” Yuxin Zhu#, Yuchen Zhang#, Dongyang He, He Yang*, Xiao-Song Xue*, Wenjun Tang*, J. Am. Chem. Soc. 2024, 146, 33249–33257.

[4] “A Thermally Populated Germylene-Based Donor-Acceptor Diradical” Yu Zhao#, Yuchen Zhang#, Tao Wang, Runbo Pei, Yue Zhao,Xiao-Song Xue*, and Xinping Wang*, Angew. Chem. Int. Ed. 2024, e202411180.

[5] “Radical 6-Endo Addition Enables Pyridine Synthesis under Metal-Free Conditions” Xiaojuan Dong#, Yingbo Shao#, Zhengyi Liu, Xia Huang, Xiao-Song Xue*, Yiyun Chen*, Angew. Chem. Int. Ed. 2024, e202410297.

[6] “Catalytic Asymmetric Oxidative Coupling between C(sp3)–H Bonds and Carboxylic Acids” Xian-Ming Liu#, Fu Li#, Tongkun Wang, Ling Dai, Yin Yang, Neng-Quan Jiang, Li-Yuan Xue, Jing-Yuan Liu, Xiao-Song Xue*, Li-Jun Xiao*, Qi-Lin Zhou*, J. Am. Chem. Soc. 2024, DOI: 10.1021/jacs.4c12544

[7] “Production of constrained L-cyclo-tetrapeptides by epimerization-resistant direct aminolysis” Huan Chen#, Yuchen Zhang#, Yuming Wen, Xinhao Fan, Nicholas Sciolino, Yanyun Lin, Leonard Breindel, Yuanwei Dai, Alexander Shekhtman*, Xiao-Song Xue*, Qiang Zhang*, Nat. Commun. 2024, 15, 5372.

[8] “Copper Difluorocarbene Enables Catalytic Difluoromethylation” Xin Zeng, Jimin Yang, Wei Deng, Xiao-Tian Feng, Hai-Yang Zhao, Lanfeng Wei, Xiao-Song Xue*, Xingang Zhang*, J. Am. Chem. Soc. 2024, 146, 16902.

[9] “Carbene-Assisted Arene Ring-Opening” Zengrui Cheng#, Haoran Xu#, Zhibin Hu, Minghui Zhu, K. N. Houk*, Xiao-Song Xue*, Ning Jiao*, J. Am. Chem. Soc. 2024, 146, 16963.

[10] “Reversal of the Regioselectivity of Iron-Promoted Hydrogenation and Hydrohalogenation of gem-Difluoroalkenes” Yu-Yang Zhang#, Yuchen Zhang#, Xiao-Song Xue*, Feng-Ling Qing*, Angew. Chem. Int. Ed. 2024, e202406324.

[11] “Photoinduced Remote C(sp3)–H Phosphonylation of Amides” Jian Wang, Yuchen Zhang, Lin Zhu, Xiao-Song Xue, Chaozhong Li*, Angew. Chem. Int. Ed. 2024, e202400856.

[12] “Formaldehyde-Mediated Hydride Liberation of Alkylamines for Intermolecular Reactions in Hexafluoroisopropanol” Shaokun Cai#, Hong Tang#, Bo Li#, Yingbo Shao, Danqi Zhang, Hanliang Zheng, Tianjiao Qiao, Xin Chu, Gang He, Xiao-Song Xue*, and Gong Chen*, J. Am. Chem. Soc. 2024, 146, 5952.

[13] “Enantioselective sulfur(VI) fluoride exchange reaction of iminosulfur oxydifluorides” Zhiyuan Peng#, Shoujun Sun#, Meng-Meng Zheng#, Yangyang Li, Xixi Li, Suhua Li, Xiao-Song Xue*, Jiajia Dong*, Bing Gao*, Nat. Chem. 2024, 16, 353.

[14] “Iridium-Catalyzed Enantioselective Transfer Hydrogenation of 1,1-Dialkylethenes with Ethanol: Scope and Mechanism” Lu Qian, Cui Yu, Lan Gan, Xixia Tang, Yulei Wang, Guixia Liu, Xuebing Leng, Zhao Sun, Yinlong Guo, Xiao-Song Xue*, and Zheng Huang*, J. Am. Chem. Soc. 2024, 146, 3427.

[15] “Enantioselective Synthesis of Planar-Chiral Sulfur-ContainingCyclophanes by Chiral Sulfide Catalyzed ElectrophilicSulfenylation of Arenes” Deng Zhu, Tong Mu, Ze-Long Li, Hui-Yun Luo, Ren-Fei Cao, Xiao-Song Xue*, and Zhi-Min Chen*, Angew. Chem. Int. Ed. 2024, e202318625.

[16] “Photoredox Nickel-Catalysed Stille Cross-Coupling Reactions” Zhenghong Zhou#, Jimin Yang#, Bo Yang, Yang Han, Lijuan Zhu*, Xiao-Song Xue*, Feng Zhu*, Angew. Chem. Int. Ed. 2023, e202314832.

[17] “Oxidative addition of an alkyl halide to form a stable Cu(III) product” Yongrui Luo#, Yuli Li#, Jian Wu, Xiao-Song Xue*, John F. Hartwig*, Qilong Shen*, Science 2023, 381, 1072-1079.

[18] “Catalyst-Substrate Helical Character Matching Determines the Enantioselectivity in the Ishihara-Type Iodoarenes Catalyzed Asymmetric Kita-Dearomative Spirolactonization” Hanliang Zheng#, Liu Cai#, Ming Pan, Muhammet Uyanik, Kazuaki Ishihara, and Xiao-Song Xue*, J. Am. Chem. Soc. 2023, 145, 7301-7312.

[19] “Reductive Catalytic Difluorocarbene Transfer via Palladium Catalysis” Xue-Ying Zhang, Shi-Ping Sun, Yue-Qian Sang, Xiao-Song Xue, Qiao-Qiao Min, Xingang Zhang*, Angew. Chem. Int. Ed. 2023, 62, e202306501.

[20] “Copper-catalysed difluorocarbene transfer enables modular synthesis” Xin Zeng, Yao Li, Qiao-Qiao Min, Xiao-Song Xue*, Xingang Zhang*, Nat. Chem. 2023, DOI: 10.1038/s41557-023-01236-8.

[21] “Copper(I)-Catalyzed Asymmetric Conjugate Addition of 1,4-Dienes to β-Substituted Alkenyl Azaarenes.” Zhi-Zhou Pan#, Deng Pan#, Jia-Heng Li, Xiao-Song Xue*, Liang Yin*, J. Am. Chem. Soc. 2023, 145, 1749-1758.

[22] “Thioethers as Dichotomous Electrophiles for Site-Selective Silylation via C-S Bond Cleavage” Shuai Chen#, Xueying Guo#, Haoran Hou, Shasha Geng, Zhengli Liu*, Yun He, XiaoSong Xue*, Zhang Feng*, Angew. Chem. Int. Ed. 2023, e202303470.

[23] “Cu/SaBox-Catalyzed Photoinduced Coupling of Acylsilanes with Alkynes” Long Zheng#, Xueying Guo#, Ying-Chao Li, Yichen Wu, Xiao-Song Xue*, Peng Wang*, Angew. Chem. Int. Ed. 2023, e202216373.

[24] “Light-Induced Divergent Cyanation of Alkynes Enabled by Phosphorus Radicals” Yanyan Zhang, Yunhong Han, Shengqing Zhu*, Feng-Ling Qing, Xiao-Song Xue*, Lingling Chu*, Angew. Chem. Int. Ed. 2022, e202210838.

[25] “Atroposelective Electrophilic Sulfenylation of N-Aryl Aminoqui-none DerivativesCatalyzed by Chiral SPINOL-Derived Sulfide” Deng Zhu#, Lu Yu#, Hui-Yun Luo, Xiao-Song Xue*, Zhi-Min Chen*, Angew. Chem. Int. Ed. 2022, e202211782.

[26] “Metal-Free Electrochemical Carboxylation of Organic Halides in the Presence of Catalytic Amounts of an Organomediator” Yanwei Wang, Zhiwei Zhao, Deng Pan, Siyi Wang, Kangping Jia, Dengke Ma, Guoqing Yang, Xiao-Song Xue*, Youai Qiu*, Angew. Chem. Int. Ed. 2022, e202210201.

[27] “Low-temperature mineralization of perfluorocarboxylic acids” Brittany Trang#, Yuli Li#, Xiao-Song Xue, Mohamed Ateia, K. N. Houk*, William R. Dichtel1*, Science 2022, 377, 839-845.

[28] “Construction of Complex Macromulticyclic Peptides via Stitching with Formaldehyde and Guanidine” Bo Li#, Zhao Wan#, Hanliang Zheng, Shaokun Cai, Han-Wen Tian, Hong Tang, Xin Chu, Gang He, Dong-Sheng Guo, Xiao-Song Xue*, Gong Chen*, J. Am. Chem. Soc. 2022, 144, 10080-10090.

[29] “Metal-Free C-H Functionalization via Diaryliodonium Salts with a Chemically Robust Dummy Ligand” Yixuan Chen#,Yuefei Gu#, Huan Meng#, Qianzhen Shao#, Zhenchuang Xu, Wenjing Bao, Yucheng Gu, Xiao-Song Xue*, Yanchuan Zhao*, Angew. Chem. Int. Ed. 2022, 61, e2022012.

[30] “Harnessing Natural Products by a Pharmacophore-Oriented Semisynthesis Approach for the Discovery of Potential Anti-SARS-CoV-2 Agents” Yuan-Fei Zhou#, Bing-Chao Yan#, Qian Yang#, Xin-Yan Long#, Dan-Qi Zhang, Rong-Hua Luo, Han-Yu Wang, Han-Dong Sun, Xiao-Song Xue*, Yong-Tang Zheng*, Pema-Tenzin Puno*, Angew. Chem. Int. Ed. 2022, 61, e2022016.

[31] “Enantioselective Synthesis of Planar-Chiral Macrocycles through Asymmetric Electrophilic Aromatic Amination” Donglei Wang#, Ying-Bo Shao#, Yunrong Chen, Xiao-Song Xue*, Xiaoyu Yang*. Angew. Chem. Int. Ed. 2022, 61, e2022010.

[32] “Highly selective synthesis of all-carbon tetrasubstituted alkenes by deoxygenative alkenylation of carboxylic acids” Yantao Li, Qianzhen Shao, Hengchi He, Chengjian Zhu*, Xiao-Song Xue*, Jin Xie*, Nat. Commun. 2022, 13, 10.

[33] “Highly γ‐Selective Arylation and Carbonylative Arylation of 3‐Bromo‐3,3‐difluoropropene via Nickel Catalysis.” Ran Cheng, Yueqian Sang, Xing Gao, Shu Zhang, Xiao-Song Xue*, Xingang Zhang*, Angew. Chem. Int. Ed. 2021, 60, 12386-12391.

[34] “The Acidities of Nucleophilic Monofluoromethylation Reagents: An Anomalous α‐Fluorine Effect.” Hanliang Zheng, Zhen Li, Jianfang Jing, Xiao-Song Xue*, Jin-Pei Cheng. Angew. Chem. Int. Ed. 2021, 60, 9401-9406.

[35] “Highly γ‐Selective Arylation and Carbonylative Arylation of 3‐Bromo‐3,3‐difluoropropene via Nickel Catalysis.” Ran Cheng, Yueqian Sang, Xing Gao, Shu Zhang, Xiao-Song Xue*, Xingang Zhang.* Angew. Chem. Int. Ed. 2021, 60, 12386-12391.

[36] “Cleaving arene rings for acyclic alkenylnitrile synthesis.” Xu Qiu, Yueqian Sang, Hao Wu, Xiao-Song Xue, Zixi Yan, Yachong Wang, Zengrui Cheng, Xiaoyang Wang, Hui Tan, Song Song, Guisheng Zhang, Xiaohui Zhang, K. N. Houk*, Ning Jiao*.Nature 2021, 597, 64-69.

[37] “Establishing for Cation and Radical Donor Ability Scales of Electrophilic F, CF3, and SCF3 transfer reagents.” Man Li, Xiao-Song Xue*, Jin-Pei Cheng. Acc. Chem. Res. 2020, 53, 182-197. (Invited review)

[38] “Radical-Mediated CC Cleavage of Unstrained Cycloketones and DFT Study for Unusual Regioselectivity.” Mingyang Wang, Man Li, Shan Yang, Xiao-Song Xue*, Xinxin Wu , Chen Zhu*. Nat. Commun. 2020, 11, 672-678.

[39] “Mechanism and Origins of Enantioselectivities in Spirobiindane-based Hypervalent Iodine(III) Induced Asymmetric Dearomatizing Spirolactonizations.” Hanliang Zheng, Yueqian Sang, K. N. Houk*, Xiao-Song Xue*, Jin-Pei Cheng. J. Am. Chem. Soc. 2019, 141, 16046-16056.

[40] “Nickel-catalyzed intermolecular oxidative Heck arylation driven by transfer hydrogenation.” Honggui Lv, Huiying Kang, Biying Zhou, Xiao-Song Xue,* Keary Engle,* and Dongbing Zhao.* Nat. Commun. 2019, 10, 5025.

[41] “Controllable Catalytic Difluorocarbene Transfer Enables Access to Diversified Fluoroalkylated Arenes.” Xia-Ping Fu#, Xiao-Song Xue#, Xue-Ying Zhang, Yu-Lan Xiao, Shu Zhang, Yin-Long Guo, Xuebing Leng, K. N. Houk*, Xingang Zhang.* Nat. Chem. 2019, 11, 948–956.

[42] “Metal-free Directed C-H Bond Activation and Borylation.” Jiahang Lv, Xiangyang Chen , Xiao-Song Xue , Binlin Zhao , Yue Zhao , Yi Lu , Jing Zhao , Wei-Yin Sun , Yong Liang, K. N. Houk*, Zhuangzhi Shi*. Nature 2019, 575, 336-340.

[43] “Ambimodal Trispericyclic Transition State and Dynamic Control of Periselectivity.”,Xiao-Song Xue#, Cooper S. Jamieson#, Marc Garcia-Borràs#, Xiaofei Dong#, Zhongyue Yang, K. N. Houk. J. Am. Chem. Soc. 2019, 141, 1217-1221.

[44] “Mechanism and Origins of Chemo- and Stereoselectivities of Aryl Iodide-Catalyzed Asymmetric Difluorinations of β-Substituted Styrenes.” Biying. Zhou, Moriana K. Haj, Eric N. Jacobsen, Houk, K. N.,* Xiao-Song Xue*. J. Am. Chem. Soc. 2018, 140, 15206-15218.

[45] “Exploration of the Synthetic Potential of Electrophilic Trifluoromethylthiolating and Difluoromethylthiolating Reagents.” Jingjing Zhang; Yang Jin-Dong; Hanliang Zheng; Xiao-Song Xue*, Herbert Mayr;* Jin-Pei Cheng. Angew. Chem. Int. Ed. 2018, 57, 12690-12695.