研究员
黎占亭
职  称: 研究员
学  历: 博士研究生
电  话: 021-54925122
职  务: 课题组长、室主任
传  真: 021-64166128
电子邮件: ztli@mail.sioc.ac.cn
通信地址: 上海市零陵路345号
个人简历

1966年出生于河南上蔡

1981.09-1985.06:郑州大学化学系本科

1987.08-1992.12:中科院上海有机所硕士和博士生(导师:吉景顺和陈庆云 研究员)

1993.03-2010.05:中科院上海有机所助理研究员、PI副研究员和研究员

1994.10-1995.12South University of Denmark化学系博士后(Jan Becher

1999.10-2000.12University of Illinois at Urbana-Champaign化学系访问学者(Steven C. Zimmerman

2010.05:复旦大学化学系教授

2020.06:特聘研究员,有机功能分子合成与组装化学重点实验室主任

研究方向

有机、大分子和高分子药物材料化学,超分子和物理有机化学:各种水溶性和生物相容性的多孔超分子和大分子材料的合成方法学,均相二维和三维有机孔道材料构建,有机多孔材料在药物输送、清除和控制释放中的应用,新的分子自组装原理和策略。

社会任职
 
获奖及荣誉

2000年:中国化学会青年化学奖

2015年:上海市自然科学奖一等奖

2016年:上海市化学化工学会庄长恭奖

2019年:中国化学会物理有机化学奖

代表论著

1.       柔性有机框架和共价有机框架及蛋白输送

(1)     J.-L. Lin, Z.-K. Wang, Z.-Y. Xu, L. Wei, Y.-C. Zhang,* H. Wang, D.-W. Zhang, W. Zhou,* Y.-B. Zhang, Y. Liu,* Z.-T. Li,* Water-Soluble Flexible Organic Frameworks That Include and Deliver Proteins. J. Am. Chem. Soc. 2020, 142, 3577-3582.

(2)     Z.-Z. Gao, Z.-K. Wang, L. Wei, G. Yin, J. Tian, C.-Z. Liu, H. Wang, D.-W. Zhang, Y.-B. Zhang, X. Li, Y. Liu,* Z.-T. Li,* Water-Soluble 3D Covalent Organic Framework that Displays an Enhanced Enrichment Effect of Photosensitizers and Catalysts for the Reduction of Protons to H2. ACS Appl. Mater. Interfaces 2020, 12, 1404-1411.

2.       超分子有机框架及药物与核酸输送

(1)    B. Yang, X.-D. Zhang, J. Li, J. Tian, Y.-P. Wu, F.-X. Yu, R. Wang,* H. Wang, D.-W. Zhang, Y. Liu,* L. Zhou,* Z.-T. Li,* In Situ Loading and Delivery of Short Single- and Double-Stranded DNA by Supramolecular Organic Frameworks.CCS Chem.2019,1, 156-165.

(2)     J. Tian, H. Wang, D.-W. Zhang, Y. Liu,* Z.-T. Li,* Supramolecular Organic frameworks (SOFs): homogeneous regular 2D and 3D pores in water. National Science Review 2017, 4, 426-436 (Invited review).

(3)     J. Tian, C. Yao, W.-L. Yang, L. Zhang, D.-W. Zhang, H. Wang, F. Zhang,* Y. Liu,* Z.-T. Li,* In situ-prepared homogeneous supramolecular organic framework drug delivery systems (sof-DDSs): overcoming cancer multidrug resistance and controlled release. Chin. Chem. Lett. 2017, 28, 798-806.

(4)     J. Tian, Z.-Y. Xu, D.-W. Zhang, H. Wang,* S.-L. Xie, D.-W. Xu, Y.-H. Ren, H. Wang, Y. Liu,* Z.-T. Li,* Supramolecular metal-organic frameworks that display high homogeneous and heterogeneous photocatalytic activity for H2 production. Nature Commun. 2016, 7, 11580.

(5)     J. Tian, T.-Y. Zhou, S.-C. Zhang, S. Aloni, M. V. Altoe, S.-H. Xie, H. Wang, D.-W. Zhang,* X. Zhao, Y. Liu,* Z.-T. Li,* Three-Dimensional Periodic Supramolecular Organic Framework Ion Sponge in Water and Microcrystals. Nature Commun. 2014, 5, 5574.

(6)     K.-D. Zhang, J. Tian, D. Hanifi, Y. Zhang, A. C.-H. Sue, T.-Y. Zhou, L. Zhang, X. Zhao,* Y. Liu,* Z.-T. Li,* Toward a Single-Layer Two-Dimensional Honeycomb Supramolecular Organic Framework in Water. J. Am. Chem. Soc. 2013, 135, 17913-17918.

3.       氢键和卤键二级结构构筑及识别和组装性能

(1)     C.-Z. Liu, S. Koppireddi, H. Wang, D.-W. Zhang,* Z.-T. Li,* Halogen Bonding Directed Supramolecular Quadruple and Double Helices from Hydrogen-?Bonded Arylamide Foldamers. Angew. Chem. Int. Ed. 2019, 58, 226-230.

(2)     P. Xin, P. Zhu, P. Su, J.-L. Hou,* Z.-T. Li,* Hydrogen Bonded Helical Hydrazide Oligomers and Polymer That Mimic the Ion Transport of Gramicidin A. J. Am. Chem. Soc. 2014, 136, 13078- 13081.

(3)     J.-L. Hou, X.-B. Shao, G.-J. Chen, Y.-X. Zhou, X.-K. Jiang, Z.-T. Li,* Hydrogen Bonded Oligohydrazide Foldamers and Their Recognition for Saccharides. J. Am. Chem. Soc. 2004, 126, 12386-12394.

(4)     D.-W. Zhang, X. Zhao, Z.-T. Li,* Aromatic Amide and Hydrazide Foldamer-Based Responsive Host-Guest Systems. Acc. Chem. Res. 2014, 47, 1961-1970.

(5)     Z.-T. Li,* J.-L. Hou, C. Li, Peptide Mimics by Linear Arylamides: A Structural and Functional Diversity Test. Acc. Chem. Res. 2008, 41, 1343-1353.

承担科研项目情况