研究员
肖吉昌
职  称: 研究员
学  历: 博士研究生
电  话: 021-54925340
职  务: 课题组长
传  真: 021-64166128
电子邮件: jchxiao@mail.sioc.ac.cn
通信地址: 上海市零陵路345号
个人简历

1988.9.-1992.7.:湖南师范大学化学系,理学学士

1992.7.-1997.7.:湖南省邵阳师范高等专科学校,讲师

1997.8.-2000.8.:上海化工研究院,工学硕士

2000.8.-2003.7.:中国科学院上海有机化学研究所,理学博士

2003.8.-2005.7.:美国爱达荷大学,博士后研究

2005.8. 至今:中国科学院上海有机化学研究所,研究员,课题组长

研究方向

1. 含氟功能分子的合成与反应:开发温和高效的氟化试剂,发展新颖氟化学反应,进行含氟药物分子和功能材料分子的合成

2. 绿色、高效分离纯化方法:针对组成复杂的混和物体系,发展高效分离试剂和绿色纯化方法

社会任职
获奖及荣誉
代表论著

1. Yu, Jiao; Lin, Jin-Hong; Yu, Donghai; Du, Ruobing; Xiao, Ji-Chang* “Oxidation of difluorocarbene and subsequent trifluoromethoxylation” Nat. Commun. 2019, 10: 5362 doi: 10.1038/s41467-019-13359-z

2. Zhang, Min; Lin, Jin-Hong; Xiao, Ji-Chang* “Photocatalyzed Cyanodifluoromethylation of Alkenes” Angew. Chem. Int. Ed. 2019, 58, 6079-6083.

3. Zhang, Wei; Chen, Jia; Lin, Jin-Hong*; Xiao, Ji-Chang*; Gu, Yu-Cheng “Rapid Dehydroxytrifluoromethoxylation of Alcohols” iScience 2018, 5, 110-117.

4. Yu, Jiao; Lin, Jin-Hong*; Xiao, Ji-Chang*Reaction of Thiocarbonyl Fluoride Generated from Difluorocarbene with AminesAngew. Chem. Int. Ed. 2017, 56, 16669-16673.

5. Zheng, Jian; Cheng, Ran; Lin, Jin-Hong; Yu, Dong-Hai; Ma, Longle; Jia, Lina; Zhang, Lan; Wang, Lu; Xiao, Ji-Chang*; Liang, Steven H.* “An Unconventional Mechanistic Insight into SCF3 Formation from Difluorocarbene: Preparation of 18F-Labeled α-SCF3 Carbonyl CompoundsAngew. Chem. Int. Ed. 2017, 56, 3196-3200.

6. Deng, Zuyong; Lin, Jin-Hong; Xiao, Ji-Chang* “Nucleophilic arylation with tetraarylphosphonium salts” Nat. Commun. 2016, 7: 10337 doi: 10.1038/ncomms10337.

7. Zheng, Jian; Wang, Lu; Lin, Jin-Hong; Xiao, Ji-Chang*; Liang, Steven H.* “Difluorocarbene-Derived Trifluoromethylthiolation and [18F]Trifluoromethylthiolation of Aliphatic ElectrophilesAngew. Chem. Int. Ed.2015, 54, 13236-13240.

8. Zhang, Cheng-Pan; Chen, Qing-Yun; Guo, Yong; Xiao, Ji-Chang*; Gu, Yu-Cheng. “Difluoromethylation and Trifluoromethylation Reagents Derived from Tetrafluoroethane β-Sultone: Synthesis, Reactivity and Applications” Coord. Chem. Rev. 2014, 261, 28-72.

9. Zhang, Cheng-Pan; Chen, Qing-Yun; Guo, Yong*; Xiao, Ji-Chang*; Gu, Yu-Cheng “Progress in fluoroalkylation of organic compounds via sulfinatodehalogenation initiation system” Chem. Soc. Rev. 2012, 41, 4536-4559.

10. Zhang, Cheng-Pan; Wang, Zong-Ling; Chen, Qing-Yun; Zhang, Chun-Tao; Gu, Yu-Cheng; Xiao, Ji-Chang*. “Copper-Mediated Trifluoromethylation of Heteroaromatic Compounds by Trifluoromethyl Sulfonium SaltsAngew. Chem. Int. Ed. 2011, 50, 1896-1900.

承担科研项目情况