1982.09-1986.06 四川师范大学 化学系 本科
1990.09-1993.02 中国科学院上海有机化学研究所 硕士(导师:黄耀曾院士)
1993.02-1996.02 中国科学院上海有机化学研究所 博士(导师:黄耀曾院士 戴立信院士)
1996.03-1996.07 中国科学院上海有机化学研究所 助理研究员
1996.08-1997.05 美国Colorado State University 博士后
1997.05-1999.04 美国Georgetown University 博士后
1999.05-1999.12 中国科学院上海有机化学研究所 副研究员
2000.01-至今 中国科学院上海有机化学研究所 研究员
2009.11-2017.01 金属有机化学国家重点实验室 主任
2009.05-2019.02 中国科学院上海有机化学研究所 副所长
2019.01-至今 中国科学院上海有机化学研究所 所长
主要从事金属有机化学研究。针对均相催化领域的选择性控制与催化效率等核心科学问题,应用边臂策略设计金属有机催化剂,发展在催化剂的活性中心区域装载配位基团(边臂)以调控其催化行为的新方法和有机合成新反应。
主要研究方向:
1. 不对称催化;
2. 烯烃聚合催化剂的设计、合成与应用;
3. 叶立德化学;
4. 天然产物全合成。
2001年 上海市科技进步一等奖 (自然科学类,第三完成人)
2002年 国家自然科学二等奖 (第三完成人)
2002年 中国科学院-拜尔青年科学家奖
2002年 获国家杰出青年基金
2003年 上海市优秀留学人才
2004年 SYNTHESIS/SYNLETT期刊奖
2004年 上海市优秀学科带头人
2005年 中国科学院优秀研究生指导教师
2006年 中国科学院研究生院优秀教师
2006年 第九届中国青年科技奖
2011年 上海市自然科学一等奖(第一完成人)
2012年 国家自然科学二等奖(第一完成人)
2012年 中国化学会黄耀曾金属有机化学奖
2015年 上海市化学化工学会庄长恭奖
2015年 上海市科技精英
2015年 中国科学院院士
2016年 全国优秀科技工作者
2019年 中国化学会手性化学奖
2021年 中国科学院先进工作者
2021年 第七届中国化学会-中国石油化工股份有限公司化学贡献奖
1. Li Zhou, Liping Li, Sudong Zhang, Xiao-kang Kuang, You-Yun Zhou,* and Yong Tang*. “Catalytic Regio- and Enantioselective Remote Hydrocarboxylation of Unactivated Alkenes with CO2”. J. Am. Chem. Soc. 2024, ASAP.
2. Sudong Zhang, Liping Li, Dingxi Li, You-Yun Zhou,* and Yong Tang*. “Catalytic Regio- and Enantioselective Boracarboxylation of Arylalkenes with CO2 and Diboron” J. Am. Chem. Soc. 2024, 146, 2888−2894.
3. Xing-Wang Han, Xun Zhang, Youyun Zhou, Aizezi Maimaitiming, Xiu-Li Sun, Yanshan Gao*, Peizhi Li, Boyu Zhu, Eugene Y.-X. Chen*, Xiaokang Kuang and Yong Tang*. Circular Olefin Copolymers Made de novo from Ethylene and α-Olefins. Nat. Commun. 2024, 15, 1462.
4. Liu-Peng Zhao, Sheng-Ye Zhang, Hua-Kui Liu, Yu-Jing Cheng, Zhi-Pan Liu*, Lijia Wang*, and Yong Tang*. Insights into Stereoselectivity Switch in Michael Addition-Initiated Tandem Mannich Cyclizations and Their Extension from Enamines to Vinyl Ethers. J. Am. Chem. Soc., 2023, 145, 15553–15564.
5. Yang Ma, Ya-Nan Zhao, Xi-Man Yang, Jun-Fang Li, Xiao-Yan Wang*, and Yong Tang*. SaBOX/Copper-Catalyzed Synthesis, Degradation, and Upcycling of a PMMA-Based Copolymer. Macromolecules 2023, 56, 7032–7042.
6. Bingxin Qu, Yanan Zhao, Ping Song, Yanshan Gao, You-Yun Zhou*, Xiu-Li Sun, Qiang Fu, Xiaoshan Ning, Junfang Li, Xiaokang Kuang, and Yong Tang*. Norbornene Monomer Effects and Mechanistic Insights in Binuclear Nickel-Catalyzed Olefin Chain Walking Copolymerizations. ACS Catal. 2023, 13, 12849–12858.
7. Liu-Peng Zhao, Peng-Juan Li, Lijia Wang* and Yong Tang*. Allenamide-Initiated Cascade [2+2+2] Annulation Enabling the Divergent Total Synthesis of (−)-Deoxoapodine, (−)-Kopsifoline D and (±)-Melotenine A. Angew. Chem. Int. Ed. 2022, 61, e202207360.
8. Ya-Ning Li, Sheng-Ye Zhang, Yang Ma, Yi-Jie Ding, Zhi-Hao Chen, Qiao-Ling Che, Long Qin, Xiu-Li Sun, Xiaohua Liu, Xiaoming Feng*, Zhi-Pan Liu*, Xiao-Yan Wang* and Yong Tang*. Hydrogen Bond Effects: A Strategy for Improving Controllability in Organocatalytic Photoinduced Controlled Radical Polymerization Targeting High Molecular Weight. ACS Catal. 2022, 12, 11606–11614.
9. Gang Ji, Zhou Chen, Xiao-Yan Wang, Xiao-Shan Ning, Chong-Jie Xu, Xing-Min Zhang, Wen-Jie Tao, Jun-Fang Li, Yanshan Gao, Qi Shen, Xiu-Li Sun*, Hao-Yang Wang, Jun-Bo Zhao, Bo Zhang, Yin-Long Guo, Yanan Zhao, Jiajie Sun, Yi Luo*, Yong Tang*. Direct Copolymerization of Ethylene with Protic Comonomers Enabled by Multinuclear Ni Catalysts. Nat. Commun. 2021, 12, 6283.
10. Li Zhou, Wen-Guang Yan, Xiu-Li Sun, Lijia Wang* and Yong Tang*. A Versatile Enantioselective Catalytic Cyclopropanation-Rearrangement Approach to the Divergent Construction of Chiral Spiroaminals and Fused Bicyclic Acetals. Angew. Chem. Int. Ed. 2020, 59, 18964−18969.
11. Zhi-Hao Chen, Yang Ma, Xiao-Yan Wang*, Xiu-Li Sun, Jun-Fang Li, Ben-Hu Zhu and Yong Tang*. A Winning Strategy for Iron-Based ATRP Using In-Situ Gener-ated Iodine as a Regulator. ACS Catal. 2020, 10, 14127−14134.
12. Hua-Kui Liu, Sunewang R. Wang, Xiang-Yang Song, Liu-Peng Zhao, Lijia Wang*, and Yong Tang. Selectivity Switch in a Rhodium(II) Carbene Triggered Cyclopentannulation: Divergent Access to Three Polycyclic Indolines. Angew. Chem. Int. Ed. 2019, 58, 4345–4349.
13. Li Zhou, Shu-Yang Yu, Yong Tang, and Lijia Wang*. Facile Stereoselective Approach to Diverse Spiroheterocyclic Tetrahydropyrans: Concise Synthesis of (+)-Broussonetine G and H. Angew. Chem. Int. Ed. 2019, 58, 15016–15020.
14. Zhi-Hao Chen, Xiao-Yan Wang*, Xiu-Li Sun, Jun-Fang Li, Ben-Hu Zhu, and Yong Tang*. Highly Efficient Atom Transfer Radical Polymerization System Based on the SaBOX/Copper Catalyst. Macromolecules 2019, 52, 9792–9798.
15. Qiong-Jie Liu, Jun Zhu, Xiang-Yang Song, Lijia Wang, Sunewang R. Wang,* and Yong Tang*. Highly enantioselective [3+2] annulation of indoles with quinones to structurally diverse benzofuroindolines. Angew. Chem. Int. Ed. 2018, 57, 3810–3814.
16. Xiao-Kang Kuang, Jun Zhu, Li Zhou, Lijia Wang, Sunewang R. Wang, and Yong Tang*. Synergetic Tandem Enantiomeric Enrichment in Catalytic Asymmetric Multi-Component Reactions (AMCRs): Highly Enantioselective Construction of Tetracyclic Indolines with Four Continuous Stereocenters. ACS Catal. 2018, 8, 4991–4995.
17. Liang-Wen Feng, Hai Ren, Hu Xiong, Pan Wang, Lijia Wang*, Yong Tang*. Reaction of donor-acceptor cyclobutanes with indoles: a general protocol for the formal total synthesis of (±)-strychnine and the total synthesis of (±)-akuammicine. Angew. Chem. Int. Ed. 2017, 56, 3055–3058.
18. Hao Chen, Lijia Wang, Feng Wang, Liu-Peng Zhao, Pan Wang, and Yong Tang*. Access to Hexahydrocarbazoles: The Thorpe–Ingold Effects of the Ligand on Enantioselectivity. Angew. Chem. Int. Ed. 2017, 56, 6942–6945.
19. Jun Zhu, Yu-Jing Cheng, Xiao-Kang Kuang, Lijia Wang, Zhong-Bo Zheng, and Yong Tang*. Highly efficient formal [2+2+2] strategy for the rapid construction of polycyclic spiroindolines: a concise synthesis of 11-demethoxy-16-epi-myrtoidine. Angew. Chem. Int. Ed. 2016, 55, 9224–9228.
20. Qiong-Jie Liu, Lijia Wang, Qi-Kai Kang, X. Peter Zhang*, and Yong Tang*. Cy-SaBOX/copper(II)-catalyzed highly diastereo- and enantioselective synthesis of bicyclic N,O acetals. Angew. Chem. Int. Ed. 2016, 55, 9220–9223.
21. Jiang-Lin Hu, Liang-Wen Feng, Lijia Wang, Zuowei Xie*, Yong Tang*, and Xiaoge Li. Enantioselective construction of cyclobutanes: a new and concise approach to the total synthesis of piperarborenine b. J. Am. Chem. Soc. 2016, 138, 13151–13154.
22. Qi-Kai Kang, Lijia Wang, Qiong-Jie Liu, Jun-Fang Li, Yong Tang*. Asymmetric H2O-nucleophilic ring opening of D–A cyclopropanes: catalyst serves as a source of water. J. Am. Chem. Soc. 2015, 137, 14594–14597.
23. Hao Xu, Jiang-Lin Hu, Lijia Wang, Saihu Liao, Yong Tang*. Asymmetric annulation of donor-acceptor cyclopropanes with dienes. J. Am. Chem. Soc. 2015, 137, 8006–8009.
24. Pan Wang, Liang-Wen Feng, Lijia Wang, Jun-Fang Li, Saihu Liao, Yong Tang*. Asymmetric 1,2-perfluoroalkyl migration: easy access to enantioenriched α-hydroxy-α-perfluoroalkyl esters. J. Am. Chem. Soc. 2015, 137, 4626–4629.
25. Jun Zhu, Yong Liang, Lijia Wang, Zhong-Bo Zheng, K. N. Houk*, Yong Tang*. Remote ester groups switch selectivity: diastereodivergent synthesis of tetracyclic spiroindolines. J. Am. Chem. Soc. 2014, 136, 6900−6903.
26. Saihu Liao, Xiu-Li Sun, Yong Tang*. Sidearm strategy for catalyst design based on bisoxazolines in the remote control of enantioselection and related. Acc. Chem. Res. 2014, 47, 2260.
27. Hu Xiong, Hao Xu, Saihu Liao, Zuowei Xie*, Yong Tang* Copper-Catalyzed Highly Enantioselective Cyclopentannulation of Indoles with Donor–Acceptor Cyclopropanes. J. Am. Chem. Soc., 2013, 135, 7851–7854.
28. Hao Xu, Jian-Ping Qu, Saihu Liao, Hu Xiong, Yong Tang* Highly Enantioselective [3+2] Annulation of Cyclic Enol Silyl Ethers with Donor-Acceptor Cyclopropanes: Accessing 3a-hydroxy [N.3.0]carbobicycles. Angew. Chem. Int. Ed. 2013, 52, 4004–4007.
29. You-Yun Zhou, Jun Li, Lin Ling, Sai-Hu Liao, Xiu-Li Sun,* Yu-Xue Li,* Li-Jia Wang, Yong Tang* Highly Enantioselective [3+3] Cycloaddition of Aromatic Azomethine Imines with Cyclopropanes Directed by p–p Stacking Interactions. Angew. Chem. Int. Ed. 2013, 52, 1452–1456.
30. Chao Deng, Li-Jia Wang, Jun Zhu, Yong Tang* A Chiral Cage-like Copper(I) Catalyst for the Highly Enantioselective Synthesis of 1,1-Cyclopropane Diesters. Angew. Chem. Int. Ed. 2012, 51, 11620–11623.
31. You-Yun Zhou, Li-Jia Wang, Jun Li, Xiu-Li Sun*, Yong Tang* Side-Arm-Promoted Highly Enantioselective Ring-Opening Reactions and Kinetic Resolution of Donor-Acceptor Cyclopropanes with Amines. J. Am. Chem. Soc. 2012, 134, 9066–9069.
32. Jun Li, Sai-Hu Liao, Hu Xiong, You-Yun Zhou, Xiu-Li Sun*, Yue Zhang, Xiaoguang Zhou, Yong Tang* Highly Diastereo- and Enantioselective Cyclopropanation of 1,2-Disubstituted Alkenes. Angew. Chem. Int. Ed. 2012, 51, 8838–8841.
33. Jiao-Long Zhou, Yong Liang, Chao Deng, Haolai Zhou, Zheng Wang, Xiu-Li Sun, Jun-Cheng Zheng, Zhi-Xiang Yu*, Yong Tang*, Tunable Carbonyl Ylide Reactions: Selective Synthesis of Dihydrofurans and Dihydrobenzoxepines. Angew. Chem. Int. Ed. 2011, 50, 7874–7878.
34. Peng Cao, Chao Deng, You-Yun Zhou, Xiu-Li Sun, Jun-Cheng Zheng, Zuowei Xie, Yong Tang*, Asymmetric Nazarov Reaction Catalyzed by Chiral Tris(oxazoline)/Copper(II). Angew. Chem. Int. Ed. 2010, 49, 4463–4466.
35. Xiao-Hong Yang, Chun-Rong Liu, Cong Wang, Xiu-Li Sun, Yang-Hui Guo, Xin-Ke Wang, Zheng Wang, Zuowei Xie, Yong Tang*, [O-NSR]TiCl3-Catalyzed Copolymerization of Ethylene with Functionalized Olefins. Angew. Chem. Int. Ed. 2009, 48, 8099–8102.
36. Sunewang R. Wang, Chun-Yin Zhu, Xiu-Li Sun, Yong Tang*, Reaction of Allylic Phosphoranes with Iron Porphyrin Carbenoids: Efficient, Selective, and Catalytic Intermolecular Formal Carbenoid Insertion into Olefinic C-H Bonds. J. Am. Chem. Soc. 2009, 131, 4192–4193.
37. Qing-Gang Wang, Xian-Ming Deng, Ben-Hu Zhu, Long-Wu Ye, Xiu-Li Sun, Chuan-Ying Li, Chun-Yin Zhu, Qi Shen, and Yong Tang*, Tandem Michael Addition/Ylide Epoxidation for the Synthesis of Highly Functionalized Cyclohexadiene Epoxide Derivatives. J. Am. Chem. Soc. 2008, 130, 5408–5409.
38. Xiu-Li Sun, Yong Tang*, Ylide-Initiated Michael Addition-Cyclization Reactions beyond Cyclopropanes. Acc. Chem. Res. 2008, 41, 937–948.
39. Long-Wu Ye, Xiu-Li Sun, Qing-Gang Wang, Yong Tang*, Phosphine Catalyzed Intramolecular Formal [3+2] Cycloaddition for the Highly Diastereoselective Synthesis of Bicyclo[n.3.0] Compounds. Angew. Chem., Int. Ed. 2007, 46, 5951–5954.