李霄鹏教授,国家自然科学基金委杰出青年基金获得者。2004年毕业于郑州大学获化学学士学位;2008年于美国克里夫兰州立大学获化学博士学位;2009-2012年,在阿克伦大学从事博士后研究。2012年起,在德克萨斯州立大学任助理教授,2016年转入南佛罗里达大学,2019年晋升终身副教授;2020年任深圳大学教授;2023年任中科院上海有机所研究员。主要研究兴趣集中在质谱仪器研制及表征技术,配位键自组装超分子化学和超分子材料。近年来,研究内容包括(1)提出了基于配位点密度的多重配位键自组装策略,实现了复杂超分子的精准构筑;(2)发展了独特的多维度质谱技术,突破了复杂超分子结构的表征瓶颈;(3)基于独特的表征方法和多重配位键自组装策略,构筑复杂功能超分子,实现有效的功能调控。共发表论文220余篇,其中多篇发表在Science、Nature、Nature Chem.、J. Am. Chem. Soc.、Angew. Chem. 、Nature Commun.、Proc. Natl. Acad. Sci. U.S.A.等学术期刊。
李霄鹏教授的系统创新工作在超分子化学和质谱领域获得了广泛的影响力。2019年由于“高度原创性和独立性的工作”获英国皇家化学会设立的以1987年三位诺贝尔化学奖得主命名的Cram Lehn Pedersen超分子化学奖(1人/每届);同时依靠独特的质谱技术与世界范围内一百多个课题组建立富有成效的合作。其它荣誉与奖项包括:美国Cottrell学者奖(2015年)、中美华人化学与化学生物学教授协会杰出青年教授奖(2017年)、英国皇家化学会会士(2017年)、深圳市杰出青年基金(2020年)、国家自然科学基金委杰出青年基金(2021年)、中国化学会超分子化学青年创新学术讲座奖(2021年)。
在过去的数十年中,超分子化学经历了迅猛发展。其中,基于配位键优异的方向性和可控性,配位自组装已经成为构筑二维和三维超分子结构的有效手段。迄今为止,此领域涌现出大量的大环和多面体组装体,然后多数结构的复杂度和组装的精准度依然不及生物大分子,由此导致功能的精妙程度也远远低于生物体系。围绕以上挑战,我们团队致力于针对以下三个方面开展了系统研究:
(1)我们发展了基于多臂配体的多重配位自组装策略,实现了二维和三维超分子结构的精准构筑。这些具有精确结构的超分子可以进一步组装成为规则有序的纳米结构,并且具有独特的性质。
(2)复杂超分子组装的不可控性和表征手段的缺乏已严重制约了此领域在功能方向的探索。针对此挑战,我们团队发展了基于多维度质谱和扫描隧道显微镜(STM)的表征技术,突破了具有大分子量和弱相互作用的超分子结构表征瓶颈。同时我们将探索制备级质谱与STM的一体化装置研制,即pMS-STM,此装置可实现大分子结构的原位可视化表征。
(3)基于多重配位自组装和独特的表征手段,我们致力于具有分子层次精准度的新材料开发,探索的范围包括主客体化学、分子识别、反应调控、仿生催化、模板合成以及生物医学。
2021 国家自然科学基金委杰出青年基金
2021 中国化学会超分子化学青年创新学术讲座奖
2020 深圳市杰出青年基金
2019 英国皇家化学会Cram Lehn Pedersen 超分子化学奖
2019 南佛罗里达大学Global Achievement Award
2019 南佛罗里达大学杰出研究奖
2017 英国皇家化学会Fellow (FRSC)
2017 中美华人化学与化学生物学教授协会杰出青年教授奖
2016 德克萨斯州立大学杰出科研奖
2015 Cottrell 学者奖
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