2003.9 - 2007.7 安徽师范大学化材学院，理学学士（导师：胡益民 教授）
2007.9 - 2012.7 中国科学院上海有机化学研究所，理学博士（导师：田伟生 研究员）
2012.7 - 2013.2 中国科学院上海有机化学研究所，研究助理
2013.2 - 2016.3 美国Scripps研究所化学系，博士后（导师： Phil S. Baran 教授）
2016.3 - 至 今 中国科学院上海有机化学研究所，研究员，课题组长，博士生导师
天然产物合成，合成方法学，药物化学
2025 上海尚思探索学者
2025 Asian Core Program Lectureship Award (Hongkong)
2023 Asian Core Program Lectureship Award (Thailand)
2022 中国科学院大学领雁奖章
2022 中国科学院青年五四奖章（首届）
2022 Natural Product Reports Emerging Investigator Lectureship
2021 国家优秀青年科学基金
2021 科学探索奖
2021 中国科学院优秀导师奖
2021 上海科技青年35人引领计划（首届）
2020 中国化学会青年化学奖
2020 中国化学会菁青化学新锐奖
2020 EurJOC Lecture Award（首届）
2017 上海市青年科技启明星计划
1. Wang, Y.; Gui, J.* Bioinspired Skeletal Reorganization Approach for the Synthesis of Steroid Natural Products. Acc. Chem. Res. 2024, 57, 568−579.
2. Yang, P.; Shen, Y.; Gui, J.* Concise Synthesis of Bufogargarizin B by a Conformation-Controlled Keletal Reorganization Approach. Nat. Commun. 2026, 17, 4156.
3. Bao, J.; Yao, L.; Tian, H.; Gui, J.* Concise Synthesis of Deoxylimonin. J. Am. Chem. Soc. 2026, 148, 4880−4885.
4. Wu, J.; Bao, J.; Deng, J.; Tian, H.; Gui, J.* Concise Syntheses of Harziane Diterpenoids by Merging Local Desymmetrization and Radical Retrosynthesis. J. Am. Chem. Soc. 2025, 147, 30599−30605.
5. Huang, G.; Zhang, X.; Gu, Y.-C.; Gui, J.* Divergent Total Syntheses of Rearranged Steroids Swinhoeisterols A–C. J. Am. Chem. Soc. 2025, 147, 20239−20245.
6. Xie, Y.; Bao, J.; Wang, Y.; Shen, Y.; Liang, Z.; Tian, H.; Gui, J.* Enantioselective Total Synthesis of (−)-Rubriflordilactone B by a Bioinspired Skeletal Reorganization Approach. J. Am. Chem. Soc. 2025, 147, 7875−7885.
7. Cen, K.; Bao, J.; Wang, X.; Tian, H.; Wang, Y.; Gui, J.* Bioinspired Divergent Synthesis of Aspersteroids A and B. J. Am. Chem. Soc. 2024, 146, 6481−6486.
8. Song, H.; Zhang, Z.; Cao, C.;* Tang, Z.;* Gui, J.;* Liu, W.* Biocatalytic Steroidal 9α-Hydroxylation and Fragmentation Enable the Concise Chemoenzymatic Synthesis of 9,10-Secosteroids. Angew. Chem. Int. Ed. 2024, 63, e202319624.
9. Wang, X.; Huang, G.; Wang, Y.; Gui, J.* Asymmetric Total Synthesis of the Rearranged Steroid Phomarol Enabled by a Biomimetic SN2′ Cyclization. J. Am. Chem. Soc. 2023, 145, 9354−9363.
10. Yang, P.; Li, Y.-Y.; Tian, H.; Qian, G.-L.; Wang, Y.; Hong, X.;* Gui, J.* Syntheses of Bufospirostenin A and Ophiopogonol A by a Conformation-Controlled Transannular Prins Cyclization. J. Am. Chem. Soc. 2022, 144, 17769−17775.
11. Wang, Y.; Tian, H.; Gui, J.* Gram-Scale Synthesis of Bufospirostenin A by a Biomimetic Skeletal Rearrangement Approach. J. Am. Chem. Soc. 2021, 143, 19576−19586.
12. Ju, W.; Wang, X.; Tian, H.; Gui, J.* Asymmetric Total Synthesis of Clionastatins A and B. J. Am. Chem. Soc. 2021, 143, 13016−13021.
13. Li, X.; Zhang, Z.; Fan, H.; Miao, Y.; Tian, H.; Gu, Y.; Gui, J.* Concise Synthesis of 9,11-Secosteroids Pinnigorgiols B and E. J. Am. Chem. Soc. 2021, 143, 4886−4890.
14. Ning, Y.; Tian, H.; Gui, J.* Biogenesis-Guided Synthesis and Structural Revision of Sarocladione Enabled by Ruthenium-Catalyzed Endoperoxide Fragmentation. Angew. Chem. Int. Ed. 2021, 60, 11222−11226 (VIP).
15. Wang, Y.; Chen, B.; He, X.; Gui, J.* Bioinspired Synthesis of Nortriterpenoid Propindilactone G. J. Am. Chem. Soc. 2020, 142, 5007−5012.
16. Deng, J.; Ning, Y.; Tian, H.; Gui, J.* Divergent Synthesis of Antiviral Diterpenes Wickerols A and B. J. Am. Chem. Soc. 2020, 142, 4690−4695.
17. Wang, Y.; Ju, W.; Tian, H.; Sun, S.; Li, X.; Tian, W.; Gui, J.* Facile Access to Bridged Ring Systems via Point-to-Planar Chirality Transfer: Unified Synthesis of Ten Cyclocitrinols. J. Am. Chem. Soc. 2019, 141, 5021−5033.
18. Wang, Y.; Ju, W.; Tian, H.; Tian, W.; Gui, J.* Scalable Synthesis of Cyclocitrinol. J. Am. Chem. Soc. 2018, 140, 9413−9416.
19. Deng, J.; Wu, J.; Tian, H.; Bao, J.; Shi, Y.; Tian, W.;* Gui, J.* Alkynes From Furans: A General Fragmentation Method Applied to the Synthesis of the Proposed Structure of Aglatomin B. Angew. Chem. Int. Ed. 2018, 57, 3617−3621.
