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2. Chen Z, Gu X, Chen H, Zhang H, Liu J, Yang X, Cai Y, Zhang M, Yan L, Yang Y, Shan B, Zhu Z, Zhang Y, Gu J*, Xu D*. RIPK1 senses S-adenosylmethionine scarcity to drive cell death and inflammation. Cell Metabolism 2025, 37(8):1732-1749. (Highlighted in Nat Cell Biol 2025, 27:1201. Highlighted in Life Metab, 2025, loaf033.)
3. Zhang N, Liu J, Guo R, Yan L, Yang Y, Shi C, Zhang M, Shan B, Li W, Gu J*, Xu D*. Palmitoylation licenses RIPK1 kinase activity and cytotoxicity in the TNF pathway. Molecular Cell 2024, 84(22):4419-4435.
4. Yang Y, Fang H, Xie Z, Ren F, Yan L, Zhang M, Xu G, Song Z, Chen Z, Sun W, Shan B, Zhu Z, Xu D*. Yersinia infection induces glucose depletion and AMPK-dependent inhibition of pyroptosis in mice. Nature Microbiology 2024, 9:2144-2159.
5. Yang Y, Zhang J, Lv M, Cui N, Shan B, Sun Q, Yan L, Zhang M, Zou C, Yuan J, Xu D*. Defective prelamin A processing promotes unconventional necroptosis driven by nuclear RIPK1. Nature Cell Biology 2024, 26(4):567-580. (News & views in Nat Cell Biol 2024, 26:508.)
6. Zhang N, Zhang J, Yang Y, Shan H, Hou S, Fang H, Ma M, Chen Z, Tan L, Xu D*. A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis. Nature Cell Biology 2024, 26(5):757-769. (Highlighted in Nat Rev Mol Cell Biol 2024, 25:420.)
7. Hou S, Zhang J, Jiang X, Yang Y, Shan B, Zhang M, Liu C, Yuan J, Xu D*. PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis. Molecular Cell 2024, 84(5):938-954. (Highlighted in Nat Chem Biol 2024, 20:263. Featured in Mol Cell 2024, 84:811.)
8. Guo R, Liu J, Min X, Zeng W, Shan B, Zhang M, He Z, Zhang Y, He K, Yuan J, Xu D*. Reduction of DHHC5-mediated Beclin 1 S-palmitoylation underlies autophagy decline in aging. Nature Structural & Molecular Biology 2024, 31(2):232-245.
9. Zhang T#, Xu D#*, Liu J, Wang M, et al, Yuan J*, Wei W*. Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation. Nature Cell Biology 2023, 25(7):950-962. (News & views in Nat Cell Biol 2023, 25:921.)
10. Zhang T#, Xu D#*, Trefts E, Lv M, et al, Pan L*, Shaw R*, Yuan J*, Wei W*. Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science 2023, 380(6652):1372-1380. (Highlighted in Science 2023, 380:1322.)
11. Yan L, Zhang T, Wang K, Chen Z, Yang Y, Shan B, Sun Q, Zhang M, Zhang Y, Zhong Y, Liu N, Gu J*, Xu D*. SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation. Nature Communications 2022, 13(1):7153.
12. Xu D#, Zhao H#, Jin M, Zhu H, Shan B, Geng J, Dziedzic S, Amin P, Mifflin L, Naito M, Najafov A, Xing J, Yan L, Liu J, Qin Y, Hu X, Wang H, Zhang M, Manuel V, Tan L, He Z, Sun Z, Lee V, Wagner G, Yuan J*. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis. Nature 2020, 587(7832):133-138.
13. Xu D#, Jin T#, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, LiW, Shan B, Naito M G, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin J, Yankner B, Yuan J*. TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging. Cell 2018, 174(6):1477-1491. (Previewed in Cell 2018, 174:1339.)
(#co-first, *corresponding)
