
1992.09-1996.06 厦门大学化学专业本科 (导师:黄培强教授)
1996.09-2001.06 中国科学院上海有机化学研究所有机化学专业博士研究生 (导师:陈庆云院士)
2002.10-2004.12 冈山大学博士后(合作导师:Kenji Uneyama)
2005.01-2006.04 冈山理科大学博士后(合作导师:Shunichi Murahashi)
2006.04-2010.04 爱达荷大学博士后(合作导师:Jean’ne M. Shreeve)
2010.04-2026.07 中国科学院上海有机化学研究所 副研究员
2026.07-至今 中国科学院上海有机化学研究所 正高级工程师
有机氟化学、表面活性剂和功能材料
1. Qian, L.; Tan, H.-D.; Dong, F.; Xiao, J.-C.; Lv, T.; Wu, Y.; Guo, Y.*; Xue, X.-S.*; Pan, Y.* “Branched Fluoroether Ethyl Surfactants as Multi-Stage Degradable Platforms for Addressing the PFAS Dilemma”, Environ. Sci. Technol. 2026, 60, 7836-7846.
2. Tian, F.; Zhang, Y.; Huang, M.*; Wu, C.; Qiu, X.; Tian, Y.; Zheng, J.*; Guo, Y.* “Fluoroether-modified Fluorinated Sulfamido Phosphocholine and its Application in AFFF”, Chin. Chem. Lett. 2026, 37, 112661.
3. Li, J.; Huang, M.*; Zhang, Y.; Zou, C.; Liu, C.*; Guo, Y.* “Synthesis and Characterization of Novel Betaine-type Fluoroether Surfactants”, Acta Chim. Sin. 2025, 83, 36−44.
4. Zhou, S.; Qian, L.; Su, Z.; Huang, M.; Lv, T.*; Wu, C.; Guo, Y.*; Xiao, J.-C.* “Synthesis and Characterization of a Series of Biofriendly Fluoroether Betaines”, Langmuir 2025, 41, 8912−8920.
5. Ni, Q.-Y.; Zhao, S.; Wu, C.; Guo, Y.*; Xiao J.-C.* “Synthesis of trans-2-(Disubstituted-amino)alkenyl Polyoxyperfluoroalkyl Ketones from Tertiary Amines and Perfluoroalkyl Ether Carboxylates Featuring “–CF2O–” Units”, Chin. J. Chem. 2025, 43, 1847−1854.
6. Xu, Y.; Guo, Y.*; Qian, L.; Su, Z.*; Chen, Q.-Y.*; Wang, J.; Jiang, L. “Fluoroether Double-chain Phosphate Surfactants: an Exploration of Alternative to Fluorotelomer Surfactants”, Langmuir 2024, 40, 1316−1326.
7. Liao, C.; Guo, S.; Huang, M.*; Guo, Y.*; Chen, Q.-Y.; Liu, C.*; Zhang, Y. “Synthesis and Properties of Fluoroether Phosphocholine”, Acta Chim. Sin. 2024, 82, 46-52.
8. Guo, S.; Guo, Y.*; Huang, M.*; Qian, L.; Su, Z.; Chen, Q.-Y.; Wu, C.; Liu C.* “Synthesis, Surface Activity, and Foamability of Two Short-chain Fluorinated Sulfonate Surfactants with Ether Bonds”, Langmuir 2023, 39, 14519−14527.
9. Zhao, S.; Guo, Y.*; Su, Z.; Wu, C.; Chen, W.; Chen, Q.-Y.* “Deoxyfluorination of Carboxylic, Sulfonic, Phosphinic Acids and Phosphine Oxides by PFECA featuring CF2O units”, Chin. J. Chem. 2021, 39, 1225-1232.
10. Zhao, S.; Guo, Y.*; Su, Z.; Cao, W.; Wu, C.; Chen, Q.-Y.* “A Series of Deoxyfluorination Reagents Featuring OCF2 Functional Groups”, Org. Lett. 2020, 22, 8634–8637.
11. Zhao, S.; Guo, Y.*, Han, E.-J.; Luo, J.; Liu, H.-M.*; Liu, C.; Xie, W.; Zhang, W.; Wang, M. “Copper(II)-catalyzed Trifluoromethylation of Iodoarenes Using Chen’s Reagent”, Org. Chem. Front. 2018, 5, 1143-1147.
12. Chen, T.; Guo, Y.*; Sun, K.; Wu, L.-Z.; Liu, W.-Q.; Liu, C.; Huang, Y.*; Chen, Q.-Y.* “Photoinduced Hydroxylperfluoroalkylation of Styrenes”, Org. Chem. Front. 2018, 5, 1045−1048.
13. Huan, F.; Chen, Q.-Y.*; Guo, Y.* “Visible Light-Induced Photoredox Construction of Trifluoromethylated Quaternary Carbon Centers from Trifluoromethylated Tertiary Bromides”, J. Org. Chem. 2016, 81, 7051−7063.
14. Li, L.; Huang, M.; Liu, C.; Xiao, J.-C.; Chen, Q.-Y.*; Guo, Y.*; Zhao, Z.-G. “2,2,2-Trifluoroethylation of Styrenes with Concomitant Introduction of a Hydroxyl Group from Molecular Oxygen by Photoredox Catalysis Activated by Visible Light”, Org. Lett. 2015, 17, 4714−4717.
15. Han, E.-J.; Sun, Y.; Shen, Q.; Chen, Q.-Y.*; Guo, Y.*; Huang, Y.-G. “Cu-mediated 2,2,2-Trifluoroethylation of Terminal Alkynes Using 1,1-Dichloro-2,2,2-trifluoroethane (HCFC-123)”, Org. Chem. Front. 2015, 2, 1379−1387.
16. Li, L.; Chen, Q.-Y.*; Guo, Y.* “Synthesis of αTrifluoromethyl Ketones via the Cu-Catalyzed Trifluoromethylation of Silyl Enol Ethers Using an Electrophilic Trifluoromethylating Agent”, J. Org. Chem. 2014, 79, 5145−5152.
17. Wang, W.; Shen, H.; Wan, X.-L.; Chen, Q.-Y.*; Guo, Y.* “Enantioselective Pd-catalyzed Allylation of Acyclic α-Fluorinated Ketones”, J. Org. Chem. 2014, 79, 6347−6353.
18. Li, L.; Chen, Q.-Y.*; Guo, Y.* “Allylic C-H alkylation with a CF3-containing nucleophile”, Chem. Commun. 2013, 49, 8764−8766.
19. Wang, Q.; Huan, F.; Shen, H., Xiao, J.-C.; Gao, M.; Yang, X.*; Murahashi, S.-I.*; Chen, Q.-Y.*; Guo, Y.* “Organocatalytic Reactions of α-Trifluoromethylated Esters with Terminal Alkenes at Room Temperature”, J. Org. Chem. 2013, 78, 12525−12531.
20. Zhang, C.-P.; Chen, Q.-Y.; Guo, Y.*; Xiao, J.-C.*; Gu, Y.-C. “Progress in Fluoroalkylation of Organic Compounds via Sulfinatodehalogenation Initiation System”, Chem. Soc. Rev. 2012, 41, 4536−4559.
21. Guo, Y.; Zhao X.; Zhang, D.; Murahashi, S.−I.* “Iridium−Catalyzed Reactions of Trifluoromethylated Compounds with Alkenes: A Csp3−H Bond Activation α-to the Trifluoromethyl Group”, Angew. Chem. Int. Ed. 2009, 48, 2047−2049.
22. Guo, Y.; Gao, H.; Twamley, B.; Shreeve, J. M.* “Energetic Nitrogen Rich Salts of N, N−bis[1(2)H−tetrazol−5−yl]amine”, Adv. Mater. 2007, 19, 2884−2888.
1. 国家重点研发计划,2023YFC3905205,高风险区域人群暴露风险评估及削减示范,2023-12至2026-11,课题负责人,所属项目《典型氟碳表面活性剂早期健康效应识别与风险预测技术》,所属专项《循环经济关键技术与装备》。
2. 福建省中科院STS计划配套项目,STS计划配套院省合作重大项目,2023T3066,两性氟调聚化合物产业化及其应用实践研究,2023-01至2025-12,项目负责人。
3. 福建省三明市科技局揭榜挂帅项目,2021-G-50,氟表面活性剂关键技术开发,2021-3至2023-6,项目负责人。
4. 中国科学院STS区域重点项目,KFJ-STS-QYZX-068,铬雾抑制剂的研究和产业化,2019-01至2020-12,项目负责人。
5. 国家自然科学基金委,面上项目,21672239,可见光促进的三氟甲基季碳中心(TFQC)的构筑研究,2017-01至2020-12,项目负责人。
6. 国家自然科学基金委,面上项目,21172241,含氟多氮化合物的合成,反应和性能,2012-01至2015-12,项目负责人。

