1992.9–1996.6 四川大学物理化学专业，本科
1996.9–2001.6 中国科学院上海有机化学研究所，理学博士（导师：林国强）
2001.8–2002.6 休斯顿大学化学系，博士后（合作导师：Jay K. Kochi）
2002.7–2007.3 布兰迪斯大学化学系，博士后（合作导师：Li Deng）
2007.3–至今 中国科学院上海有机化学研究所，研究员
天然产物合成，生物酶催化，手性药物
上海市青年科技启明星（2008年）
中国科学院相关人才计划择优支持（2010年）
ACP Lectureship Award（2015-2017年）
中国化学会维善天然产物合成化学奖（2017年）
Thieme Chemistry Journal Award（2018年）
上海市优秀学术带头人（2020年）
国家高层次人才（万人计划，2022年）
中国科学院朱李月华优秀教师奖（2022年）
(1) Longxing Wang, Lili Zhu, Lingyong Wang, Min Shi, Huilei Yu, Ran Hong, Relay Oxidation with Engineered P450 BM3 and Aldo-Keto Reductase: Chemoenzymatic Synthesis of Erythrina Alkaloids. ACS Catalysis (2026) 16: 7025–7034.
(2) Mingyuan Lai, Yu Weng, Jian Wei, Xin-Yi Lu, Zhengyu Huang, Hangcheng Li, Longhao Huang, Zhijun Zhang, Lili Zhu, Jian-He Xu, Ran Hong, Hui-Lei Yu, Designing an oxidase toolbox for site-directed oxidation of taxanes. Nature Communications (2026) 17: e841
(3) Yu-Cong Zheng, Yong Mao, Qiang Geng, Fu-Long Li, Xu-Dong Kong, Yi-Ke Qi, Lin Zhang, Qi Chen, Zhi-Jun Zhang, Ran Hong, Yi-Lei Zhao, Hui-Lei Yu, Jian-He Xu, Flipping of a Non-productive Substrate Binding Conformation Facilitates Hydroxynitrile Lyase Catalyzed Hydrocyanation. Angewandte Chemie International Edition (2025) 64: e202515778
(4) Bingbing Zhang, Kuan Zheng, Ran Hong, Biomimetic Synthesis of Chejuenolides A–C by a Cryptic Lactone-Based Macrocyclization: Stereochemical Implications in Biosynthesis. ACS Central Science (2023) 9: 84–92.
(5) Zhuwei Ruan, Min Wang, Chen Yang, Lili Zhu, Zhishan Su, Ran Hong, Total Synthesis of (+)-Hinckdentine A: Harnessing Noncovalent Interactions for Organocatalytic Bromination. JACS Au (2022) 2: 793–800.
(6) Kuan Zheng, Ran Hong, The Fruit of Gold: Biomimicry in the Syntheses of Lankacidins. Accounts of Chemical Research (2021) 54: 3438–3451.
(7) Lin Yang, Luyao Kong, Qi Gu, Shunjie Shao, Guo-Qiang Lin, Ran Hong, Stereoselective Access to Polypropionates Expedited by the Double Hydroboration of Allenes: Total Synthesis of Antitumor (−)-Pironetin. CCS Chemistry (2021) 3: 769–779.
(8) Yu-Cong Zheng, Fu-Long Li, Zuming Lin, Guo-Qiang Lin, Ran Hong, Hui-Lei Yu, Jian-He Xu, Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes. ACS Catalysis (2020) 10: 5757–5763.
(9) Kuan Zheng, Defeng Shen, Ran Hong, Biomimetic Synthesis of Lankacidin Antibiotics. Journal of the American Chemical Society (2017) 139: 12939–12942.
(10) Li Zhai, Xuechao Tian, Chao Wang, Qi Cui, Wenhua Li, Sha-Hua Huang, Zhi-Xiang Yu, Ran Hong, Construction of Morphan Derivatives by Nitroso–Ene Cyclization: Mechanistic Insight and Total Synthesis of (±)-Kopsone. Angewandte Chemie International Edition (2017) 56: 11599-11603.
(11) Lin Yang, Zuming Lin, Sha-Hua Huang, Ran Hong, Stereodivergent Synthesis of Functionalized Tetrahydropyrans Accelerated by Mechanism‐Based Allylboration and Bioinspired Oxa-Michael Cyclization, Angewandte Chemie International Edition (2016), 55, 6280-6284.
(12) Jie Ouyang, Rui Yan, Xianwei Mi, Ran Hong, Enantioselective Total Synthesis of (−)-Hosieine A. Angewandte Chemie International Edition (2015) 54: 10940-10943.
(13) Lin Yang, Guoli He, Ruifeng Yin, Lili Zhu, Xiaoxia Wang, Ran Hong, Synthesis of Polyketide Stereoarrays Enabled by a Traceless Oxonia-Cope Rearrangement. Angewandte Chemie International Edition (2014) 53: 11600.
(14) Yan Wang, Kuan Zheng, Ran Hong, Chiral Silver Phosphate-Catalyzed Cycloisomeric Kinetic Resolution of α-Allenic Alcohols. Journal of the American Chemical Society (2012) 134: 4096–4099.
(15) Yan Wang, Lili Zhu, Yuying Zhang, Ran Hong, Bioinspired and Concise Synthesis of (±)-Stemoamide. Angewandte Chemie International Edition (2011) 50: 2787-2790.
