1985-1989 北京大学技术物理系 学士
1989-1992 中科院上海有机化学研究所 硕士
1992-1995 中科院上海有机化学研究所 博士
1995.8-1996.9 纽约大学 博士后
1996.9-1997.9 中科院上海有机化学研究所 助理研究员
1997.9-1999.11 中科院上海有机化学研究所 副研究员
1999.11-至今 中科院上海有机化学研究所 研究员
现任中国科学院上海有机化学研究所生命有机国家重点实验室主任、课题组长。
具有重要生理活性的复杂寡糖、糖缀合物及其它天然产物，如：动物糖胺聚糖(如肝素)和特征肿瘤抗原、微生物抗生素、植物和海洋糖苷(如皂甙和黄酮甙)等的全合成、合成方法学和化学生物学。其它研究内容还涉及：中药；天然产物的分离鉴定；糖基转移酶和糖苷水解酶抑制剂；兼亲分子的超分子化学等。
Fellow of the Royal Society of Chemistry (FRSC)
“万人计划”第一批科技创新领军人才（2014年）
上海市人民政府青年科技杰出贡献奖 （2013年）
第九届上海市自然科学牡丹奖 （2012年）
礼来杰出科研奖 （2012）
上海市化学化工学会庄长恭奖（2010）
国家自然科学奖二等奖（2010年）
中国化学会青年化学奖(1998年)；
中科院杰出青年(2000年)；
国家杰出青年基金(1999年)；
上海市科技启明星和学科带头人基金(1999 2002 2006年)；
首批新世纪百千万人才工程国家级人选(2004年)；
无锡药明康德生命化学研究奖(2007)；
上海市自然科学二等奖(2006年)等
1. Gold (I)-Catalyzed glycosylation with glycosyl o-alkynylbenzoates as donors. B. Yu,* Acc. Chem. Res. 2018,51,507-516.
2. Inhibition of cancer stem cell like cells by a synthetic retinoid. J. Chen,X. Cao,Q. An,Y. Zhang,K. Li,W. Yao,F. Shi,Y. Pan,Q. Jia,W. Zhou,F. Yang,F. Wei,N. Wang,* B. Yu,* Nature Commun. 2018,9:1406.
3 .Amipurimycin,total synthesis of the proposed structures and diastereoisomers. S. Wang,J. Sun,Q. Zhang,X. Cao,Y. Zhao,G. Tang,B. Yu,* Angew. Chem. Int. Ed. 2018,57,2884-2888.
4. Gold-catalyzed glycosylation on the synthesis of complex carbohydrate-containing natural products. W,Li,B. Yu,* Chem. Soc. Rev. 2018,47,7954–7984.
5. Total synthesis of echinoside A,a representative triterpene glycoside of sea cucumbers. X. Chen,X. Shao,W. Li,X. Zhang,B. Yu,* Angew. Chem. Int. Ed. 2017,56,7648-7652.
6. Synthesis of bradyrhizose oligosaccharides relevant to the Bradyrhizobium O-antigen. W. Li,A. Silipo,L. B. A. Gersby,M.-A. Newman,A. Molinaro,* B. Yu,* Angew. Chem. Int. Ed. 2017,56,2092-2096.
7. Total synthesis of periploside A,a unique pregnane hexasaccharide with potent immunosuppressive effects. X. Zhang,Y. Zhou,J. Zuo,B. Yu,* Nat. Commun. 2015,6,5879.
8. Total Synthesis of Linckosides A and B,the Representative Starfish Polyhydroxysteroid Glycosides with Neuritogenic Activities. D. Zhu,B. Yu,* J. Am. Chem. Soc. 2015,137,15098-15101.
9. A Modular Approach to the Total Synthesis of Tunicamycins. J. Li,B. Yu,* Angew. Chem. Int. Ed. 2015,54,6618–6621.
10.O-Glycosylation methods in the total synthesis of complex natural glycosides. Y. Yang,* X. Zhang,B. Yu,* Nat. Prod. Rep. 2015,32,1331-1355.
11.Molecular matchmaking between the popular ‘weight loss’ herb Hoodia gordonii and GPR119,a potential drug target for metabolic disorder. S. Zhang,Y. Ma,J. Li,J. Ma,B. Yu,* X. Xie,* Proc. Natl. Acad. Sci. USA 2014,111,14571-14576.
12.Total synthesis of nucleoside antibiotic A201A. S. Nie,W. Li,B. Yu,* J. Am. Chem. Soc. 2014,136,4157-4160.
13.Mechanistic insights into the gold(I)-catalyzed activation of glycosyl ortho-alkynylbenzoates for glycosidation. Y. Tang,J. Li,Y. Zhu,Y. Li,B. Yu,* J. Am. Chem. Soc. 2013,135,18396-18405.
14.Assembly of naturally occurring glycosides,evolved tactics and glycosylation methods. B. Yu,* J. Sun,X. Yang,Acc. Chem. Res. 2012,45,1227-1236.
15.Total synthesis of landomycin A,a potent antitumor angucycline antibiotic. X. Yang,B. Fu,B. Yu,* J. Am. Chem. Soc. 2011,133,12433-12435.
16.An efficient approach to the synthesis of nucleosides,gold(I)-catalyzed N-glycosylation of pyrimidines and purines with glycosyl ortho-alkynylbenzoates. Q. Zhang,J. Sun,Y. Zhu,F. Zhang,B. Yu,* Angew. Chem. Int. Ed. 2011,50,4933–4936.
17.Characterization of the isochromen-4-yl-gold(I) intermediate in the gold(I)-catalyzed glycosidation of glycosyl o-alkynylbenzoates and enhancement of the catalytic efficiency thereof. Y. Zhu,B. Yu,* Angew. Chem. Int. Ed. 2011,50,8329–8332.
18.Total synthesis and structural revision of TMG-chitotriomycin,a specific inhibitor of insect and fungal?-N-acetylglucosaminidases Y. Yang,Y. Li,B. Yu,* J. Am. Chem. Soc. 2009,131,12076-12077.
19.Total synthesis of Lobatoside E,a potent antitumor cyclic triterpene saponin. C. Zhu,P. Tang,B. Yu,* J. Am. Chem. Soc. 2008,130,5872-5873
20.Total synthesis of Candicanoside A,a potent antitumor saponin bearing a rearranged steroid side chain. P. Tang,B. Yu,* Angew. Chem. Int. Ed. 2007,46,2527-2530.
