2018年10月26日,『生命有机化学国家重点实验室』和『手性科学伙伴国家重点实验室』在香港理工大学举行了伙伴实验室年度学术交流会议。黄国贤教授首先介绍了伙伴实验室正式通过科技部的验收,并更名为『化学生物学及药物研发国家重点实验室 The State Key Laboratory of Chemical Biology and Drug Discovery』,在研究方向、硬件和人才布局等方面都有了进一步的发展。21位研究人员分别就各自课题的最新研究进展做了学术报告,并对其中展现的热点科学问题和技术手段进行了热烈讨论。同时,经过八年的不断交流,合作课题也越来越广泛和深入。
学术报告如下:
- (1)马大为 研究员:Total Synthesis of Bioactive Alkaloids
- (2)梁润松 教授:Human Arginase Drug Development: an Update
- (3)俞飚 研究员:Chemical Synthesis of Biologically Significant Marine Saponins
- (4)赵燕湘 教授:Structural Study of the Mammalian Beclin2 to Delineate its Distinct Roles in Regulating Autophagy and GPCR Trafficking
- (5)唐功利 研究员:Biosynthesis of High-active Alkaloids Bicyclomycin and CC-1065
- (6)周銘祥 教授:Design of Specific Notch1 Inhibitors
- (7)陈以昀 研究员:Visible-Light-Induced Bond-Forming and Bond-Cleavage Reactions and Their Biological Applications
- (8)陈声 教授:Research Updates on mcr-1, a Plasmid Mediated Colistin Resistance Gene
- (9)周佳海 研究员:Discovery of a Natural-product Herbicide With a New Mode of Action
- (10)黄文健 博士:Gold Catalysis and Silver-mediated Bioconjugation
- (11)曹春阳 研究员:Antiepilepsy effects of small peptide targeting BK channels (a+beta4) subtype
- (12)李建華 博士:EPH receptor B2 augments cancer stemness and drug resistance via a Wnt positive signaling loop in hepatocellular carcinoma
- (13)余永耀 教授:Enantioselective Ruthenium-Catalyzed Intramolecular Amidation of C(sp3)-H Bond to Form γ-Lactams
- (14)潘李锋 研究员:Structural Characterizations of the Autophagy Receptor NDP52 and TAX1BP1
- (15)姚锺平 博士:Chiral Recognition by Mass Spectrometry
- (16)康经武 研究员:Micro Column Affinity Chromatography for Drug Target Identification
- (17)柯子斌 博士:CTCF in Liver Cancer and Drug Discovery of Novel CTCF inhibitors
- (18)王婧 研究员:Mechanism Based MITF Inhibition by Selective Small Molecular for Melanoma Treatment
- (19)赵倩 博士:Chemical Proteomics Approaches for Drug Target Identification and Beyond
- (20)房鹏飞 研究员:Adaptation to Non-canonical Function by Dynamic Adjustment in Lysyl-tRNA Synthetases
- (21)马聰 博士:Targeting Protein-Protein Interactions for Antimicrobial Discovery
参会代表合影