October 2，2024

Congrats to Yong Liu and Hongda Chen for the latest publication in J. Am. Chem. Soc. We have disclosed a synergistic asymmetric molecular Cu catalysis with Pd nanoparticle catalysis. Enabled by this synergistic dual Cu/Pd catalyst system, an enantioselective coupling between readily available aldimine esters and alkynes is successfully achieved, affording a diverse set of α-quaternary allyl amino ester derivatives in good yields with excellent enantioselectivities.