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姓 名:
 殷亮
性 别:
 男
职 称:
 研究员
学 历:
 博士研究生
电 话:
 021-54925168
传 真:
 021-64166128
电子邮件:
 liangyin@sioc.ac.cn
个人主页:
 
通讯地址:
 上海市零陵路345号 200032

简历:

2000.09—2004.06   南开大学化学学院本科 
2004.09—2007.06   南开大学化学学院硕士研究生 
2007.10—2010.09   日本东京大学药学部博士课程 (Prof. Masakatsu Shibasaki and Prof.Motomu Kanai) 
2010.10—2011.03   日本东京大学药学部JSPS博士后 (Prof. Motomu Kanai) 
2011.04—2012.03   美国哈佛大学化学与化学生物学系博士后 (Prof. E. J. Corey) 
2012.04—2014.10   日本微生物化学研究所JSPS外国人博士后 (Prof. Masakatsu Shibasaki and Dr. Naoya Kumagai) 
2014.10—至今     中国科学院上海有机化学研究所研究员、课题组长 


研究方向:

新型简单易得手性配体和有机小分子催化剂的设计与合成
新型不对称催化反应的开发与应用 
具有重大生物活性的天然产物的全合成以及相关合成类似物的药物化学筛选 


专家类别:
研究员

职务:
课题组长

社会任职:

获奖及荣誉:

1.2007南开大学优秀硕士毕业论文一等奖 
2.2007日本政府文部科学省奖学金 
3.2010日本学术振兴会JSPS博士和博士后奖学金(DC2PD 
4.2012日本学术振兴会JSPS外国人博士后奖学金 

代表论著:

1. Feng Zhong, Wen-Jun Yue, Hai-Jun Zhang, Cheng-Yuan Zhang, and Liang Yin* “Catalytic Asymmetric Construction of Halogenated Stereogenic Carbon Centers by Direct Vinylogous Mannich-Type Reaction” J. Am. Chem. Soc. 2018, 140, 15170–14175.
2. Hai-Jun Zhang, and Liang Yin* “Asymmetric Synthesis of ???-Unsaturated ?-Lactones through Copper(I)-Catalyzed Direct Vinylogous Aldol Reaction” J. Am. Chem. Soc. 2018, 140, 12270–12279.
3. Hai-Jun Zhang, Alexander W. Schuppe, Shi-Tao Pan, Jin-Xiang Chen, Bo-Ran Wang, Timothy R. Newhouse,* and Liang Yin* “Copper-Catalyzed Vinylogous Aerobic Oxidation of Unsaturated Compounds with Air” J. Am. Chem. Soc. 2018, 140, 5300–5310.
4. Hai-Jun Zhang, Chang-Yun Shi, Feng Zhong, and Liang Yin* “Direct Asymmetric Vinylogous and Bisvinylogous Mannich-Type Reaction Catalyzed by a Copper(I) Complex” J. Am. Chem. Soc. 2017, 139, 2196–2199.
5. Liang Yin, Lennart Brewitz, Naoya Kumagai,* and Masakatsu Shibasaki* “Catalytic Generation of ?-CF3 Enolate: Direct Catalytic Asymmetric Mannich-Type Reaction of ?-CF3 Amide” J. Am. Chem. Soc. 2014, 136, 17958–17961.
6. Liang Yin, Hisashi Takada, Shaoquan Lin, Naoya Kumagai,* and Masakatsu Shibasaki* “Direct Catalytic Asymmetric Vinylogous Conjugate Addition of Unsaturated Butyrolactones to ???-Unsaturated Thioamides” Angew. Chem. Int. Ed. 2014, 53, 5327–5331.
7. Liang Yin, Youmei Bao, Naoya Kumagai,* and Masakatsu Shibasaki* “Catalytic Asymmetric Hydrophosphonylation of Ketimines” J. Am. Chem. Soc. 2013, 135, 10338–10341.
8. Liang Yin, Hisashi Takada, Naoya Kumagai,* and Masakatsu Shibasaki* “Direct Catalytic Asymmetric Vinylogous Mannich-Type Reaction of ?-Butenolides with Ketimines” Angew. Chem. Int. Ed. 2013, 52, 7310–7313.
9. Liang Yin, Motomu Kanai* and Masakatsu Shibasaki* “A Facile Pathway to Enantiomerically-Enriched 3-Hydroxy-2-Oxindoles: Asymmetric Intramolecular Aryl-Transfer Reaction to Ketones Catalyzed by a Palladium-DifluorPhos Complex” Angew. Chem. Int. Ed. 2011, 50, 7620–7623.
10.Liang Yin, Motomu Kanai* and Masakatsu Shibasaki* “Nucleophile Generation via Decarboxylation: Asymmetric Construction of Contiguous Trisubstituted and Quaternary Stereocenters through a Cu(I)-Catalyzed Decarboxylative Mannich-Type Reaction” J. Am. Chem. Soc. 2009, 131, 9610–9611.

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