NMR Chemical Shifts of Trace Impurities: Industrially Preferred Solvents Used in Process and Green Chemistry

Nicholas R. Babij, Elizabeth O. McCusker, Gregory T. Whiteker*, Belgin Canturk, Nakyen Choy, Lawrence C. Creemer, Carl V. De Amicis, Nicole M. Hewlett, Peter L. Johnson, James A. Knobelsdorf, Fangzheng Li, Beth A. Lorsbach, Benjamin M. Nugent, Sarah J. Ryan, Michelle R. Smith, and Qiang Yang

DOI: 10.1021/acs.oprd.5b00417

Enantioselective Total Synthesis of (−)-Hunterine A Enabled by a Desymmetrization/Rearrangement Strategy

Elliot F. Hicks, Kengo Inoue, and Brian M. Stoltz*

DOI: 10.1021/jacs.3c13590

Electrochemical Impedance Spectroscopy─A Tutorial

Alexandros Ch. Lazanas and Mamas I. Prodromidis*

DOI: 10.1021/acsmeasuresciau.2c00070

Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies

Daniel W. Robbins, Mark A. Noviski, Ying Siow Tan, Zef A. Konst, Aileen Kelly, Paul Auger, Nivetha Brathaban, Robert Cass, Ming Liang Chan, Ganesh Cherala, Matthew C. Clifton, Stefan Gajewski, Timothy G. Ingallinera, Dane Karr, Daisuke Kato, Jun Ma, Jenny McKinnell, Joel McIntosh, Jeff Mihalic, Brent Murphy, Jaipal Reddy Panga, Ge Peng, Janine Powers, Luz Perez, Ryan Rountree, Austin Tenn-McClellan, Arthur T. Sands, Dahlia R. Weiss, Jeffrey Wu, Jordan Ye, Cristiana Guiducci, Gwenn Hansen, and Frederick Cohen*

DOI: 10.1021/acs.jmedchem.3c01007

A Dual Cobalt and Photoredox Catalysis for Hydrohalogenation of Alkenes

Shotaro Shibutani, Kazunori Nagao*, and Hirohisa Ohmiya*

DOI: 10.1021/jacs.3c10133

Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects

Yue Li, Le Tao, Qiong Wang, Fengbang Wang, Gang Li, and Maoyong Song*

DOI: 10.1021/envhealth.3c00052

Thompson Sampling─An Efficient Method for Searching Ultralarge Synthesis on Demand Databases

Kathryn Klarich, Brian Goldman, Trevor Kramer, Patrick Riley, and W. Patrick Walters*

DOI: 10.1021/acs.jcim.3c01790

Regiodivergent Ring-Expansion of Oxindoles to Quinolinones

Hendrik L. Schmitt, Den Martymianov, Ori Green, Tristan Delcaillau, Young Seo Park Kim, and Bill Morandi*

DOI: 10.1021/jacs.3c12119

Activity of Gut-Derived Nisin-like Lantibiotics against Human Gut Pathogens and Commensals

Zhenrun J. Zhang*, Chunyu Wu, Ryan Moreira, Darian Dorantes, Téa Pappas, Anitha Sundararajan, Huaiying Lin, Eric G. Pamer*, and Wilfred A. van der Donk*

DOI: 10.1021/acschembio.3c00577

Opportunities and Challenges for Machine Learning-Assisted Enzyme Engineering

Jason Yang, Francesca-Zhoufan Li, and Frances H. Arnold*

DOI: 10.1021/acscentsci.3c01275